实用肝脏病杂志 ›› 2022, Vol. 25 ›› Issue (3): 423-426.doi: 10.3969/j.issn.1672-5069.2022.03.030

• 肝癌 • 上一篇    下一篇

机器人与开腹手术治疗肝内胆管细胞癌患者近期疗效研究*

马虎成, 任昊桢, 汤宁, 王帅, 张玉衡, 施晓雷   

  1. 210008 南京市 南京大学医学院附属鼓楼医院肝胆胰中心
  • 收稿日期:2021-07-02 出版日期:2022-05-10 发布日期:2022-05-17
  • 通讯作者: 施晓雷,E-mail: njsxl2000@163.com
  • 作者简介:马虎成,男,35岁,医学博士,主治医师。主要从事肝胆胰良恶性疾病的诊治与研究。E-mail:mahucheng1986@163.com
  • 基金资助:
    *国家自然科学基金资助项目(编号:81902957);十三五南京市卫生青年人才培养工程基金资助项目(编号:QRX17130)

Robotic hepatectomy in treatment of patients with intrahepatic cholangiocarcinoma: A preliminary study

Ma Hucheng, Ren Haozhen, Tang Ning, et al   

  1. Centre of Hepatobiliary and Pancreatic Surgery, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing 210008, Jiangsu Province, China
  • Received:2021-07-02 Online:2022-05-10 Published:2022-05-17

摘要: 目的 比较机器人与传统开腹手术行肝叶切除术治疗肝内胆管细胞癌(ICC)患者的安全性和短期疗效。方法 2019年1月~2020年12月我院诊治的ICC患者27例,其中9例接受机器人手术,18例接受传统开腹肿瘤根治术,比较两组手术情况。结果 两组均完成肿瘤根治术;机器人组和开腹组患者手术时间【(198±32)分对(215±74)分】、术中出血量【200(100,250) ml对(275(200,300)ml】和术中输血次数(0次对2次)均无统计学差异(P>0.05);机器人组和开腹组患者肿瘤直径【4.0(2.5,5.5) cm 对6.3(3.9,6.5) cm】、R0切除率(100.0%对88.0%)和淋巴结转移率(44.4%对38.9%)比较,差异无统计学意义(P>0.05);机器人组术后卧床时间和住院日分别为2(1,2.5)d和7(4,8)d,显著短于开腹组【分别为3(1.8,3.5)d和11(8,12)d,P<0.05】,机器人组住院费用为11.3(9.1,13.5)万,与开腹组的10.1(8.8,11.5)万比,无统计学差异(P>0.05);两组术后并发症发生率为11.1%和27.8%,无统计学差异(P>0.05)。结论 开展机器人肿瘤根治术治疗ICC患者安全,术后恢复快。

关键词: 肝内胆管细胞癌, 肝叶切除术, 机器人, 外科治疗

Abstract: Objective The purpose of this study was to compare the safety of robotic and laparotomy hepatectomy in dealing with patients with intrahepatic cholangiocarcinoma (ICC). Methods A total of 27 patients with ICC were enrolled in the Hepatobiliary and Pancreatic Surgery Center, Drum Tower Hospital between January 2019 and December 2020, and 9 patients received robotic hepatectomy and 18 open surgery. Results The radical surgery was finished in all patients in both groups; there were no significant differences respect to operation time [(198±32)min vs. (215±74) min], intraoperative blood loss [200 (100,250) ml vs.(275(200,300) ml] and intraoperative blood transfusion (0.0% vs. 11.1%, all P>0.05); there were no significant differences as respect to maximal tumor diameter [4.0 (2.5,5.5) cm vs. 6.3 (3.9, 6.5) cm], R0 resection rate (100.0% vs. 88.0%) and lymph node metastasis rate (44.4% vs. 38.9%) between the two groups (P>0.05); the postoperative bed time and hospitalization stay in patients receiving robotic surgery were 2(1, 2.5)d and 7(4, 8)d, significantly shorter than [3(1.8, 3.5)d and 11(8, 12)d, respectively, P<0.05] in patients receiving open surgery, and there was no significant difference respect to medical costs [113.0 (91.0, 135.0) thousands in robotic vs. 101.0(880.0, 115.0) thousands in open surgery, P>0.05); there was no significant difference in post-operational complications (11.1% vs. 27.8%) in the two groups (P>0.05). Conclusion The robotic hepatectomy in dealing with patients with ICC in safe, with a rapid postoperative recovery.

Key words: Intrahepatic cholangiocarcinoma, Hepatectomy, Robot, Surgery