骨髓间充质干细胞治疗肝脏疾病研究进展

doi:10.3969/j.issn.1672-5069.2015.02.032

摘要/Abstract

摘要： 骨髓间充质干细胞在适当的条件下可以分化为有功能的成熟肝细胞,为治疗终末期肝病提供了新思路。本文综述了骨髓间充质干细胞治疗肝硬化、肝细胞癌和肝衰竭等肝脏疾病的机制、临床应用价值、移植途径等方面的进展,介绍了在实际应用中存在的问题,并展望了该领域的应用前景。

关键词: 骨髓间充质干细胞, 肝硬化, 肝细胞癌, 肝衰竭, 治疗进展

Abstract: Bone marrow mesenchymal stem cells （BMSCs） can be differentiated into functional and mature hepatocytes in the proper conditions. The application of BMSCs may provides a new approach for end-stage liver disease. In this review,we summarized the progress in the application of BMSCs for treating patients with liver diseases such as cirrhosis,hepatocellular carcinoma （HCC） and liver failure. We’ll also discuss the transplantation and the existing problems in the practice.

Key words: Bone marrow mesenchymal stem cells, Cirrhosis, Hepatocellular carcinoma, Liver failure, Transplantation

姜华, 高建鹏. 骨髓间充质干细胞治疗肝脏疾病研究进展[J]. 实用肝脏病杂志, 2015, 18(2): 217-220.

Jiang Hua, Gao Jianpeng. Progress in bone marrow mesenchymal stem cells in the treatment of patients with liver diseases[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2015, 18(2): 217-220.

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