实用肝脏病杂志 ›› 2015, Vol. 18 ›› Issue (1): 47-50.doi: 10.3969/j.issn.1672-5069.2015.01.012

• 肝硬化 • 上一篇    下一篇

多层螺旋CT门静脉造影与B超检查预测肝硬化食管静脉曲张出血的对比研究*

刘文娜, 宁涛, 戴光荣, 王剑, 段世玲, 冯义朝, 郝婷婷   

  1. 716000 陕西省延安市 延安大学附属医院消化内科二病区(刘文娜,戴光荣,冯义朝,郝婷婷); 普外科二病区(宁涛); CT室(王剑); B超室(段世玲)
  • 收稿日期:2014-07-23 出版日期:2015-12-17 发布日期:2015-12-17
  • 通讯作者: 戴光荣,E-mail:daiguangrong6810@sina.cn
  • 作者简介:刘文娜,女,27岁,硕士研究生。主要从事肝脏疾病的诊治研究。
  • 基金资助:
    延安大学附属医院研究生创新基金项目(编号:10YJ11)

A comparative study of multi-slice spiral CT portography and B-mode ultrasonography in patients with cirrhosis for predicting esophageal variceal bleeding

Liu Wenna, Ning Tao, Dai Guangrong, et al   

  1. Department of Gastroenterology,Affiliated Hospital,Yan'an University,Yan'an 716000, Shaanxi Province,China
  • Received:2014-07-23 Online:2015-12-17 Published:2015-12-17

摘要: 目的 比较多层螺旋CT门静脉造影(MSCTP)三维重建技术和B超门静脉血流动力学检查对食管静脉曲张出血(EVB)预测的准确性。方法 收集60例同时行MSCTP和B超检查的肝硬化患者的临床资料,记录其实际出血的患者例数。根据胃左静脉(LGV)>0.61 cm和门静脉血流量(PBF)>1098.36 ml/min为预测出血的标准,记录两种方法预测出血的实际发生例数。根据预测出血例数/实际出血例数,分别计算两种方法对出血的检出率,并比较MSCTP和B超检查与胃镜检查结果的一致性。结果 在60例患者中实际出血28例;LGV>0.61cm对出血的检出率为89.29%,PBF>1098.36 ml/min的检出率为60.71%,说明分别以MSCTP和B超检查对出血的检出率差异有统计学意义(x2=6.095,P=0.029);在28例实际出血的患者中,通过胃镜检查发现有静脉曲张出血26例,未发现出血2例;采用McNemar检验发现,MSCTP与胃镜检查对EVB预测结果的差异无统计学意义(P=1.000);采用Kappa系数法分析,显示这两种方法的吻合度差异具有显著性(吻合系数K=0.781,P=0.000);B超与胃镜检查对EVB预测结果的差异具有统计学意义(P=0.012),采用Kappa系数法分析,显示这两种方法的吻合度差异无显著性(吻合系数K=0.038,P=0.747)。结论 MSCTP对预测EVB有更好的检出率,并且MSCTP与胃镜检查结果具有较高的一致性,因而对EVB具有重要的预测价值。

关键词: 肝硬化, 食管静脉曲张出血, CT门静脉造影, B超

Abstract: Objective To evaluate the accuracy of predicting esophageal variceal bleeding (EVB) in patients with liver cirrhosis with three-dimensional reconstruction by multi-slice spiral CT portography (MSCTP) and hemodynamic determination of portal vein by B ultrasonography. Methods The clinical data of 60 patients with cirrhosis who were simultaneously examined by MSCTP and B ultrasonography were collected in this study. The gastroscopy was conducted in patients with EVB. Results In 60 with liver cirrhosis, the actual number of bleeding was 28. When LGV>0.61 cm and PBF>1098.36 ml/min were determined as the cut-off value for EVB, the accurate rates by MSCTP and ultrasonography were 89.29% and 60.71%, respectively(x2=6.095,P=0.029);26 out of 28 patients with EVB was confirmed by gastroscopy, and no esophageal varices bleeding in the other 2 cases;MSCTP and gastroscopy had no significant difference in predicting EVB (P=1.000) as determined by McNemar test,and Kappa coefficient analysis showed substantial consistency of these two methods (matching coefficient K=0.781,P=0.000);While there was a significant difference between ultrasonography and gastroscopy in predicting EVB(P=0.012),and Kappa coefficient analysis showed slight consistency of these two methods (matching coefficient K=0.038,P=0.747). Conclusion MSCTP can predict EVB,and has a good consistency with gastroscopy.

Key words: Cirrhosis, Esophageal varices bleeding, CT portography, Ultrasonography