关键词: 肝细胞癌, 3.0T 磁共振成像, 多排螺旋CT成像, 动态增强扫描, 诊断

Abstract: Objective To investigate the diagnostic value of 3.0T multi-phase dynamic magnetic resonance （MR） enhanced scan and multi-slice spiral CT three-phase augmentation in patients with hepatocellular carcinoma（HCC）. Methods Ninety-eight patients with suspected primary liver cancer were admitted to our hospital between September 2015 and September 2017,and all of them received MR imaging （MRI） and CT scan. Their efficacy of diagnosis was evaluated by histopathological examination. Kappa test was used to analyze the consistency between diagnostic scores by three doctors' determination. The receiver operating characteristic curve （ROC） was used and the area under the curve （AUC） was calculated to determine the diagnostic efficacy of the imaging findings. Results 86 case out of 98 patients were diagnosed with HCC by pathological confirmation. 97 cancerous foci were found in the 86 patients with HCC by imaging check-up, and 32 were less than 1.0 cm;MRI found 31（96.9%）,while CT found 26（81.3%,P<0.05） out of the 32 foci <1.0 cm;both MRI and CT found other 65 foci >1.0 cm;kappa test analysis showed that the HCC diagnostic scores by three physicians were consistent with the k=0.77,0.82,0.74（P>0.05）;ROC analysis demonstrated that the AUC were 0.962 and 0.824,respectively,（t=3.106,P<0.05） by MRI and CT,with the sensitivity,specificity and accuracy being 99.0%,91.0% and 96.2% by MRI,significantly superior to 93.8%,72.0% and 85.3% by CT scan（x²=19.587,P<0.05）. Conclusion The multi-phase dynamic contrast-enhanced 3.0T MR scan could show the fine morphology and enhancement features of HCC lesions,which might has a better diagnostic efficacy in finding small hepatic cancer.

Key words: Hepatocellular carcinoma, 3.0T MR, Multi-slice spiral CT, Dynamic enhanced scan, Diagnosis