实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (4): 321-324.doi: 10.3969/j.issn.1672-5069.2011.04.037
• 会议纪要 • 上一篇
段晓燕,范建高
收稿日期:
2011-03-21
出版日期:
2011-08-10
发布日期:
2016-04-15
通讯作者:
范建高,E-mail: fanjiangao@gmail.com
作者简介:
段晓燕 女,32岁,博士研究生,住院医师。主要从事脂肪肝和肝癌的基础研究。
Received:
2011-03-21
Online:
2011-08-10
Published:
2016-04-15
段晓燕,范建高. 2010 年AASLD年会脂肪性肝病纪要[J]. 实用肝脏病杂志, 2011, 14(4): 321-324.
[1] CSAK T,GANZ M,KODYS K,et al. Inflammasome activation occurs in NASH in vivo and it is mediated by fatty acids through sensitization to LPS-induced inflammasome activation in hepatocytes[J]. Hepatology,2010,52(S1):77A. [2] ZHANG Y,LIU SH,LEE CH,et al. Mice lacking thioesterase superfamily member1(THEM1)/STARD14 are protected against diet-induced hepatic steatosis: role of white adipose inflammation[J]. Hepatology,2010,52(S1):1043A-1044A. [3] KAMADA Y,KISO S,YOSHIDA Y,et al. Estrogen deficiency enhanced the progression of steatohepatitis with increased macrophage infiltration in mice fed with high fat and high cholesterol diet[J]. Hepatology,2010,52(S1):1051A. [4] BANZ V,CLARIDGE LC,KAVANAGH DP,et al. Kupffer cell dependent IL-17 secretion and Th17 cell recruitment drives murine steatohepatitis[J]. Hepatology,2010,52(S1):1045A-1046A. [5] THAPALIYA S,BERK MP,DIXON LJ,et al. Role of BAX activation in steatohepatitis development in vivo[J]. Hepatology, 2010,52(S1):1048A. [6] DIXON LJ,BERK MP,THAPALIYA S,et al. Caspase 1-mediated regulation of fibrogenesis in diet-induced steatohepatitis[J]. Hepatology,2010,52(S1):77A. [7] RANGWALA F,GUY CD,JIUYI LU,et al. increased production of sonic hedgehog by ballooned hepatocytes: implications for fibrosis progression in NASH[J]. Hepatology,2010,52(S1):78A. [8] KUMAMOTO R,UTO H,TANOUE S,et al. Dietary fructose rather than dietary fat affects liver tumor incidence induced by diethylnitrosamine administration in rats[J]. Hepatology,2010,52(S1):1042A. [9] SYDOR S,GU Y,SOWA JP,et al. Western diet enhances expression of death receptors and fatty acid transporters in a mouse model of 70% hepatectomy and leads to increased cell proliferation in the liver[J]. Hepatology,2010,52(S1):1056A. [10] IKEJIMA K,YAMAGATA H,ARAI K,et al. Depletion of natural killer T cells increases the susceptibility to dietary-induced steatohepatitis in mice[J]. Hepatology,2010,52(S1):1041A. [11] SAWADA K,OHTAKE T,HASEBE T,et al. Disturbance of hepatic and intestinal Toll-like receptor signal pathway in high-fat diet induced NAFLD model mice[J]. Hepatology, 2010,52(S1):1061A-1062A. [12] JI C,LAU MY,PETROVIC LM,et al. liver specific deletion of the key chaperone GRP78/BIP aggravates a spectrum of acute and chronic stress-induced liver injury[J]. Hepatology,2010,52(S1):78A. [13] SOON RK,YAN JS,GRENERT JP,et al. Stress signaling in the methionine-choline-deficient model of murine fatty liver disease[J]. Hepatology,2010,52(S1):1043A. [14] KON K,IKEJIMA K,SAITO H,et al. Trans-fatty acid induces apoptosis of hepatocytes by enhancement of oxidative stress in steatotic liver of KK-AY mice[J]. Hepatology,2010,52(S1): 1053A-1054A. [15] BAFFY G,NEUSCHWANDER-TETRI BA. Genetics and environment in the progression of NAFLD[J]. Hepatology, 2010,52(S1):110A [16] DASARATHY S,YANG Y,RUNKANA A,et al. Differential effects of diet and genetic background on hepatic microRNA expression in diet induced NAFLD[J]. Hepatology,2010,52(S1): 1058A-1059A. [17] PASRICHA S,KENNEY-HUNT J,CHEVERUD J,et al. Quantitative trait loci(QTL)analysis of fatty liver disease[J]. Hepatology,2010,52(S1):1054A. [18] FRANCQUE S,VERLINDEN W,BROSIUS I,et al. Vascular hyporeactivity in steatosis-induced portal hypertension is mediated by a special cyclooxygenase 2-related mechanism[J]. Hepatology,2010,52(S1):1040A-1041A. [19] COULON SH,GEERTS AM,CASTELEYN C,et al. Presence of liver angiogenesis and upregulation of VEGF in a mice model of non-alcoholic steatohepatitis(NASH)[J]. Hepatology,2010,52(S1):1062A-1063A. [20] BUCK M,CHOJKIER M. TNF-α induced phosphorylation of C/EBPβ serine-239 is critical for the development of obesity and fatty liver[J]. Hepatology,2010,52(S1):77A. [21] MOYLAN CA,ABDELMALEK MF,PANG H,et al. Signals from the fibrostic liver in patients with NAFLD may promote diabetes and obesity[J]. Hepatology,2010,52(S1):1049A-1050A. [22] LANTHIER N,MOLENDI-COSTE O,CANI PD,et al. Cross-talk between kupffer cells and adipose tissue in the pathogenesis of IR[J]. Hepatology,2010,52(S1):1045A. [23] STOLL JM,SHRESTHA S,SCAPA EF,et al. Resistance to diet induced diabetes due to reduced hepatic glucose production in mice lacking phosphatidylcholine transfer protein(PC-TP)[J]. Hepatology,2010,52(S1):1053A. [24] SONG M,SCHUSCHKE D,ZHOU Z,et al. High fructose feeding induces copper deficiency: a novel mechanism for obesity related fatty liver[J]. Hepatology,2010,52(S1):1058A. [25] SIDDIQUI MS,SIDDIQUI MB,GREEN RM. Metabolic syndrome resistant A/J mice fed a high fat diet down regulate SREBP-1c activity and function[J]. Hepatology,2010,52(S1):1063A. [26] SYN WK,CHOI SS,LIASKOU E,et al. osteopontin promotes NAFLD progression[J]. Hepatology,2010,52(S1):77A. [27] SKOIEN R,POWELL EE, MELINO M,et al. Fatty acids induce hepatocyte senescene in vitro: implications for pathogenesis in NASH[J]. Hepatology,2010,52(S1):1044A-1045A. [28] KANURI G,SPRUSS A,WAGNERBERGER S,et al. Critical role of plasminogen activator inhibitor(PAI-1),microsomal triglyceride transfer protein(MTTP)and NKT cells in the onset of fructose-induced steatosis in mice[J]. Hepatology,2010,52(S1):1049A. [29] ARIAZU E,LEUNG TM,PAGANOS S,et al. SPP1 contributer to NASH in mice fed a methionine-choline deficient diet[J]. Hepatology,2010,52(S1):1053A. [30] KANG HW,COHEN DE. Interactions between thioesterase superfamily member 2(THEM2)and phosphatidylcholine transfer protein(PC-TP)limit hepatic triglyceride secretion[J]. Hepatology,2010,52(S1):1056A. [31] SYDOR S,SOWA JP,TRECKMANN J,et al. Increased expression of FABP-1 and CFLIPL by free fatty acid treatment is associated with reduced death-receptor mediated apoptosis and ERK-activation in human primary hepatocytes[J]. Hepatology, 2010,52(S1):1056A-1057A. [32] ZUfiIGA S,FIRRINCIELI D,LASNIER E,et al. Invalidation of the vitamin D nuclear receptor promotes liver steatosis[J]. Hepatology,2010,52(S1):1021A-1119A. [33] LOKMAN KA,PLEVRIS-PAPAIOANNOU A,BAREN JP,et al. The effect of free fatty acid and reactive oxygen species on CIDEB expression in in vitro model of steatosis[J]. Hepatology,2010,52(S1):1059A-1060A. [34] SOFTIC S,KIRBY M,SHROYER N,et al. Insulin signaling mediates hepatic steatosis through fatty acid transport proteins (FATPS)in a U-shaped dose dependent manner[J]. Hepatology,2010,52(S1):1060A. [35] IMAJO K,FUJITA K,NOZAKI Y,et al. Decrease in hepatic microsomal triglyceride transfer protein mRNA levels and pathological progression induced by lipopolysaccharide in a murine NASH model[J]. Hepatology,2010,52(S1):1060A-1061A. [36] VIKER K,KRISHNAN A,SANDERSON SO,et al. The fast food diet mouse-a novel small animal model of NASH with progressive fibrosis and high fidelity to the human condition[J]. Hepatology,2010,52(S1):1046A-1047A. [37] WU J,SCHIE IW,VEMURI M,et al. A new mouse model of NASH created by feeding diet containing conjugated linoleic acid[J]. Hepatology,2010,52(S1):1057A. [38] FOLLI F,CHAVEZ A,CASIRAGHI F,et al. The baboon as a model of NAFLD. Increased intra-hepatic fat content and impairment in the insulin signaling cascade in obese/IR non-human primates[J]. Hepatology,2010,52(S1):1059A. [39] GUPTA NA,KWUN J,KIRK AD,et al. Role of GLP-1R agonists in decreasing hepatic steatosis and apoptosis in ob/ob mice undergoing ischemia reperfusion injury[J]. Hepatology, 2010,52(S1):1041A-1042A. [40] RECTOR RS, UPTERGROVE G,MORRIS M,et al. Attenuation of weight gain through daily exercise versus caloric restriction and prevention of NAFLD in hyperphagic OLETF rats[J]. Hepatology,2010,52(S1):1042A. [41] SOLFIS-MUFOOZ P,GARCA-RUIZ I,GMEZ-IZQUIERDO E,et al. Effects of melatonin on the mitochondrial respiratory chain(MRC)complexes and liver histology in ob/ob mice with NAFLD[J]. Hepatology,2010,52(S1):1043A. [42] UENO T,NAKAMURA A,NAKAMURA T,et al. Adiponectin suppresses endoplasmic reticulum(ER)stress in nonalcoholic steatohepatitis(NASH)[J]. Hepatology,2010,52(S1):1044A. [43] LIANG M,PECORA BS,WANG X,et al. Raltegravir prevents hepatic steatosis due to HIV protease inhibitors by enhancing autophagy[J]. Hepatology,2010,52(S1):1046A. [44] OKADA Y,NISHIKAWA T,JO M,et al. Rosuvastatin improves hepatic inflammation and fibrosis through the inhibition of oxidative stress in rats NASH model[J]. Hepatology,2010,52(S1): 1047A. [45] ADAR T,LICHTENSTEIN Y,LALAZAR G,et al. Induction of CD4+CD25+FOXP3+ regulatory T cells by oral administration of IgG-enhanced colostrum suppressed the chronic inflammatory state in ob/ob mice alleviating the insulin resistance and liver injury[J]. Hepatology,2010,52(S1):1047A. [46] MELLS JE,FU PP,HANDY JA,et al. Daily administration of liraglutide ameliorates the deleterious effects of high-fructose corn syrup and trans-fat feeding in C57BL6 mice-implications for NAFLD[J]. Hepatology,2010,52(S1): 1048A. [47] SALAMONE F,VOLTI GL. Silybin improves liver injury and adipose tissue inflammation in mice with NAFLD[J]. Hepatology,2010,52(S1):1049A. [48] TREVASKIS JL,GRIFFIN P,WITTMER C,et al. Glucagon-like peptide-1(GLP-1)receptor agonism improves biochemical and histopathological indices of NASH in mice[J]. Hepatology,2010,52(S1):1061A. [49] LAVALLARD V,BONNAFOUS S,ROUSSEAU D,et al. Role of autophagy in hepatocyte death in NASH[J]. Hepatology,2010,52(S1):1050A-1051A. [50] MAZO DF,PEREIRA IV,LIMA VM,et al. S-nitroso-N-acetylcysteine (SNAC),a nitric oxide donor,modulated hepatic stellate cells(HSCS)activity and has antifibrogenic properties in experimental nonalcoholic steatohepatitis(NASH)[J]. Hepatology,2010,52(S1):1052A. [51] DERDAK Z,VILLEGAS KA,WANDS JR. The P53 inhibitor, pifithrin-alpha P-nitro attenuates NAFLD in mice[J]. Hepatology,2010,52(S1):1052A. [52] ADAR T,LALAZAR G,ZOLOTAROV L,et al. Increased AKT phosphorylation alleviates insulin resistance and its associated liver injury: a synergistic effect of oral insulin and beta glycolipid[J]. Hepatology,2010,52(S1):1054A-1055A. [53] KAJIKAWA S,IMADA K,TAKEUCHI T,et al. The therapeutic effect of eicosapentaenoic acid against hepatic fibrosis in a rat model of NASH[J]. Hepatology,2010,52(S1):1055A. [54] LEE JI, LEE JW,KIM YS,et al. Effect of sylimarin on methinnie-choline deficient diet induced NASH in IR rats[J]. Hepatology,2010,52(S1):1055A. [55] MALHI H,KROPP E,KAUFMAN RJ. C/EBP homologous protein(CHOP)protects mice from NASH[J]. Hepatology,2010,52(S1):1057A. [56] ADAR T,ZOLOTAROV L,LALAZAR G,et al. Steroid induced insulin resistance and its associated liver injury can be reversed by beta-glucosylceramide. A novel hepatoprotective co-adjuvant treatment strategy for steatohepatitis[J]. Hepatology, 2010,52(S1):1057A-1058A. [57] TREVASKIS JL,GRIFFIN P,TATARKIEWICZ K,et al. Exenatide exhibits significant antisteatotic actions in diabetic LEPOB/LEPOB mice compared to sitagliptin and pioglitazo-ne[J]. Hepatology,2010,52(S1):1050A. [58] JUN DW,CHO WK,KWON HJ,et al. Prevention of free fatty acid induced hepatic lipotoxicity by carnitine through restoration of mitochondrial dysfunction[J]. Hepatology,2010,52(S1): 1062A. [59] SETSHEDI M,TONG M,FENG D,et al. Ceramide inhibitors and PPAR agonists ameliorate alcohol-induced steatohepatitis in an ex-vivo liver slice culture model[J]. Hepatology,2010,52(S1):1063A. [60] HAN Y,JING Q,FRANCIS H,et al. Emerging roles of microRNAs in the control of apoptosis and transformation in hepatobiliary cells during alcoholic liver disease[J]. Hepatology, 2010,52(S1):379A. [61] LIN CW,TSAI MH,CHEN X,et al. Enhanced autophagy alleviated ethanol-induced fatty liver in mouse[J]. Hepatology, 2010,52(S1):379A-380A. [62] AMBADE A,CATALANO D,MANDREKAR P. Targeting HSP90,a molecular chaperone in alcoholic liver injury: inhibition of LPS-induced TNFα production[J]. Hepatology,2010,52(S1):380A. [63] LEVIN I,NATH B,KURT-JONES EA,et al. Activation of hypoxia inducible factor 1-alpha in hepatocytes requires toll like receptor 4 dependent pathways and results in steatosis in a mouse model of chronic ethanol challenge[J]. Hepatology,2010,52(S1):380A-381A. [64] DERDAK Z,VILLEGAS KA,WANDS JR. Fibrosis-related transcription factor early growth response-1(EGR-1)promotes steatosis in the liver of ethanol-fed long-evans rats by activating sterol regulatory element binding protein-1(SREBP1)[J]. Hepatology,2010,52(S1):1112A. [65] KIRPICH I,ZHANG JW,GOBEJISHVILI L,et al. Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic HDACS 1,7,9,10,11 and up-regulation of HDAC 3[J]. Hepatology,2010,52(S1):1113A. [66] HOWARTH DL,SADLER KC. ATF-6 and the unfolded protein response play a key role in acute ethanol-induced steatosis in zebrafish[J]. Hepatology,2010,52(S1):1113A. [67] DEGRFI D,LEMMERS A,GUSTOT T,et al. Correlation between CCL2(MCP-1),neutrophils recruitment and disease severity in alcoholic hepatitis: a potential IL-17 dependent pathway[J]. Hepatology,2010,52(S1):1113A-1114A. [68] KI SH,PARK O,ZHENG MQ,et al. Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic plus binge ethanol feeding: role of STAT3[J]. Hepatology,2010,52(S1):1115A. [69] TR?PO E,GUSTOT T,DEGRE D,et al. Common polymorphism in PNPLA3 gene in associated with stetosis and cirrhosis in alcoholic liver disease[J]. Hepatology,2010,52(S1):381A. [70] LOUVET A,ARTRU F,WARTEL F,et al. Long-term data in severe alcoholic hepatitis: alcohol relapse is the key factor of survival[J]. Hepatology,2010,52(S1):381A. [71] ALTAMIRANO J,BATALLER R,FAGUNDES C,et al. Acute kidney injury(AKI)negatively impacts short-term survival in patients with alcoholic hepatitis: implications for therapy[J]. Hepatology,2010,52(S1):1108A. [72] LOUVET A,ARTRU F,DIAZ E,et al. Prognostic scores are efficient in patients with severe alcoholic hepatitis treated with corticosteroids: comparison of available models[J]. Hepatology, 2010,52(S1):1108A-1109A. [73] LOUVET A,ARTRU F,WARTEL F,et al. A response-guided therapy for a better management of patients severe alcoholic hepatitis treated with corticosteroids[J]. Hepatology,2010,52(S1):1109A. [74] HIRAMINE Y,IMAMURA Y,UTO H,et al. Alcohol drinking patients and the risk of fatty liver in Japanese men[J]. Hepatology,2010,52(S1):1109A-1110A. [75] AMATHIEU R,NAHON P,TRIBA MN,et al. Metabolomic approach by proton NMR spectroscopy of blood serum for the assessment of chronic liver failure in alcoholic cirrhosis patients[J]. Hepatology,2010,52(S1):1110A. [76] ELLEFSON WM,LAKNER AM,MCKILLOP LH,et al. Hormonal imprinting influences early alcohol-induced liver injury[J]. Hepatology,2010,52(S1):1110A-1111A. [77] LOUVET A,DELTENRE P,ARTRU F,et al. Hepatic venous pressure gradient in severe alcoholic hepatitis is not associated with survival:a prospective study[J]. Hepatology,2010,52(S1):1119A. [78] ASRANI SK,LARSON JJ,BENSON JT,et al. Survival of patients with alcoholic hepatitis: a population-based study[J]. Hepatology,2010,52(S1):1111A. [79] SINGAL AK,ANDERSON KE,KUO YF. Hepatitis C virus infection and increased severity of acute alcoholic hepatitis in a large national inpatient data sample[J]. Hepatology,2010,52(S1):1112A. [80] THULUVATH PJ,NGUYEN GC. Impact of HCV and hepatic encephalopathy on the outcome of patients admitted with alcoholic hepatitis[J]. Hepatology,2010,52(S1):1114A. [81] LIANGPUNSAKUL S. Clinical characteristics and mortality of hospitalized alcoholic hepatitis patients in the United States[J]. Hepatology,2010,52(S1):1114A. |
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