实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (2): 135-137.doi: 10.3969/j.issn.1672-5069.2011.02.019

• 论著 • 上一篇    下一篇

SPECT判断切肝量及其与肝癌术后肝功能不全的关系

孙永刚,李建生,荚卫东,许戈良,程义壮,马金良,余继海   

  1. 230001 合肥市 安徽医科大学附属省立医院肝脏外科肝癌研究中心(孙永刚,李建生,荚卫东,许戈良,马金良,余继海);核医学科(程义壮)
  • 收稿日期:2011-01-04 出版日期:2011-04-10 发布日期:2016-04-15
  • 通讯作者: 李建生,E-mail:lijiansheng1953@163.com
  • 作者简介:孙永刚 男,31岁,硕士研究生。主要从事肝脏外科学研究

Estimation of hepatic resection volume by SPECT in patients with primary liver cacer

SUN Yonggang,LI Jiansheng,JIA Weidong,et al.   

  1. Centre for the Study of Liver Cancer,Department of Hepatic Surgery,Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001, P.R.China
  • Received:2011-01-04 Online:2011-04-10 Published:2016-04-15

摘要: 目的 探讨单光子发射型计算机断层显像(SPECT)评估肝脏储备功能。方法 在46例肝癌患者于术前行SPECT核素扫描,记录5min心肝相关指数、清除指数、受体指数和高峰值。结果 术后31例肝功能恢复良好患者术前HH15与15例肝功能不全患者有统计学差异(P<0.05),而ICGR15和Child-Pugh分级无统计学差异(P均>0.05);HH15≥0.533患者术后肝功能不全发生率明显高于HH15<0.533患者(P<0.05)。结论 HH15是评估肝脏储备功能的敏感指标。

关键词: 肝癌, 肝叶切除, 肝功能不全, 单光子发射型计算机断层显像

Abstract: Objective To investigate the evaulation of liver reserve by single-photon emission computed tomography(single photon emission computed tomography,SPECT). Method SPECT were conducted in 46 patients with primary liver cancer and the 5 min heart and liver-related index(5 minutes heart liver index,HLI),clearance index(blood clearance index,HH15),receptor index(receptor index,LHL15)and the peak value were measured. Results Preoperative HH15 in 31 patients with postoperative good liver function tests was much lower than that in 15 patients with liver failure(P<0.05),while ICGR15 and Child-Pugh scores were not significantly different in the two groups(P>0.05);when HH15≥0.533,the patients had much higher liver failure incidence as compared to those with HH15<0.533(P<0.05). Conclusion HH15 is a sensitive indicator of liver functional reserve.

Key words: Hepatoma, Hepatic dysfunction, Single-photon emission computed tomography, Liver functional reserve