实用肝脏病杂志 ›› 2010, Vol. 13 ›› Issue (5): 350-351.doi: 10.3969/j.issn.1672-5069.2010.05.011

• 论著 • 上一篇    下一篇

终末期肝病模型评估失代偿期肝硬化患者中短期预后的价值探讨

李平   

  1. 239300 安徽省天长市人民医院感染病科
  • 收稿日期:2010-05-10 出版日期:2010-10-10 发布日期:2016-04-18
  • 作者简介:李平 男,47岁,副主任医师。主要从事感染性疾病与肝病的临床工作。E-mail:lp13955079078@sina.com

Implication of model of end-stage liver disease in assessment of short and middle terms prognosis in patients with decompensated liver cirrhosis

LI Ping.   

  1. Department of Infectious Disease,Tianchang People’s Hospital,Tianchang 239300,Anhui Province,China
  • Received:2010-05-10 Online:2010-10-10 Published:2016-04-18

摘要: 目的 采用终末期肝病模型(MELD)评估失代偿期肝硬化患者中短期预后。方法 对167例失代偿期肝硬化患者进行回顾性分析,应用受试者工作曲线(ROC)下面积(AUC)来比较MELD和CTP评分在3个月、6个月和12个月时对预后预测的准确性。结果 在随访3月、6月和12月时,分别有23例、42例和66例患者死亡;死亡患者的MELD和CTP评分比生存患者高(P<0.001);MELD得分越高,死亡的危险越大。结论 MELD与CTP评分均能准确地评估失代偿期肝硬化患者的中短期预后。

关键词: 失代偿期肝硬化, 终末期肝病模型, 预后

Abstract: Objective To investigate the implication of the model of end-stage liver disease(MELD)in assessment of short and middle term prognosis in patients with decompensated liver cirrhosis. Method 167 patients with decompensated liver cirrhosis admitted to our hospital were studied and followed up at least for one year. MELD and Child-Turcotte-Pugh(CTP)score were calculated at presentation. The receiver operation characteristic curves(ROC)and the area under ROC were used to determine the ability of predicting three,six and twelve month mortality. Result There were 23,42 and 66 dead cases at month 3,6 and 12,respectively;the MELD and CTP scores in dead were much higher than in survivals(P<0.001);the higher the MELD score,the higher risk the dead. Conclusion Both MELD and CTP scores can accurately predict the short and middle term prognosis of patients with decompensated liver cirrhosis.

Key words: Liver cirrhosis, The model of end-stage liver disease, Prognosis