Abstract: Objective To observe the effects of comprehensive insulation measures on changes of temperature in patients with hepatocellular carcinoma（HCC） underwent hepatectomy and on postoperative recovery. Methods Sixty patients with HCC were randomly divided into control and observation group. 30 cases in control group were given regular insulation measures,while the other 30 cases in observation were treated with comprehensive insulation measures when they underwent hepatectomy. The temperature variation,emergence agitation and shiver,the incidence of postoperative complications such as cough and fever,the leaving bed time and average hospitalization days were compared between the two groups. Results The temperatures of patients in observation group after liver parenchyma transaction and during recovery period were（36.0±0.43）℃ and （36.1±0.37）℃,respectively,while they were（35.7±0.33）℃ and（35.8±0.20）℃ in control group,and the incidence of hypothermia during operation in observation group was significantly lower than that in the control group（P<0.01）. The incidences of shiver and emergence agitation during recovery period were 10.0% and 13.3%,respectively in observation group,while they were 40.0% and 36.7%,respectively in control group. Incidence of postoperative cough and fever were 13.3% and 10.0%, respectively in observation group, while they were 36.7% and 33.3%,respectively in control group （P<0.05）.The first leaving bed time was（26.8±3.57）hours in observation group,while it was （41.2±4.44）hours in control group（P<0.05）. The mean hospital stay was（8.1±1.79）d in observation group,while it was （10.2±1.59）d in control group（P<0.05）. ConclusionsComprehensive insulation measures can effectively maintain relatively normal body temperature in patients with HCC during hepatectomy. It can also reduce the incidence of emergence agitation and shiver,as well as the occurrence of postoperative complications. Furthermore, comprehensive insulation measures play an active role in fast-track surgery （FTS） of patients with HCC.

Key words: Hepatocellular carcinoma, Comprehensive insulation measures, Fast-track surgery