Abstract: Objective The purpose of this study was to analyze the diagnostic efficacy of color Doppler ultrasonography and magnetic resonance cholangiopancreatography (MRCP) in patients with cholecystolithiasis. Methods A retrospective analysis was performed on the clinical data of 78 patients with suspected cholecystolithiasis who were admitted to our hospital between June 2018 and March 2022. All patients underwent color Doppler ultrasonography and MRCP, and thereafter received cholecystectomy. Results Out of the 78 patients with suspected cholecystolithiasis, the histopathological examination after operation showed gallbladder stones in 71 cases (91.0%), including typical gallbladder stones in 51 cases(65.4%), full gallbladder stone in 13 cases (16.7%), multiple stones in 4 cases (5.1%) and silt-like stones in 3 cases (3.8%), and without stones in 7 cases (9.0%); the diagnostic rate of gallbladder stones by MRCP was 83.3%, much higher than 64.1%(P＜0.05) by ultrasonography; the diagnostic sensitivity and specificity by MRCP were 90.1% and 85.7%, both significantly higher than 67.6% and 71.4% (P<0.05) by color Doppler ultrasonography; the detection rates of stones at 0.5-1.0 cm by MRCP was 43.6%, much higher than 32.1%(P＜0.05) by ultrasonography. Conclusion The MRCP could detect smaller gallstones effectively, which might help clinicians to deal with appropriately at some special circumstances.

Key words: Cholecystolithiasis, Magnetic resonance cholangiopancreatography, Color Doppler ultrasonography, Diagnostic performance