Journal of Practical Hepatology ›› 2023, Vol. 26 ›› Issue (2): 297-300.doi: 10.3969/j.issn.1672-5069.2023.02.037

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Hepatitis B virus reactivation during biologics therapy

Li Yangzhou, Lu Shuang   

  1. Department of Infectious Diseases, Affiliated Hospital, Guizhou Medical University, Guiyang 550001, Guizhou Province, China
  • Received:2021-09-27 Online:2023-03-10 Published:2023-03-21

Abstract: Objective With the wide application of biologics, the hepatitis B virus (HBV) reactivation have been increasingly become a problem. The patients with HBV reactivation may suffer from liver failure, which might lead to death. The screening, prophylactic antiviral therapy and surveillance for the patients at a risk of HBV reactivation have become the consensus of major related guidelines. In this article, we reviewed the population risk stratification, mechanism by which the HBV reactivated, and the prophylactic antiviral agents.

Key words: Hepatitis B virus, Biologics, Reactivation