分段注射对比剂CT增强扫描提高乙型肝炎肝硬化患者肝静脉显影效果研究*

doi:10.3969/j.issn.1672-5069.2021.06.026

Abstract

Abstract: Objective The aim of this study was to investigate the impact of segmented injection of contrast agent, ioversol, on hepatic vein imaging by CT angiography (CTA) in patients with hepatitis B-induced liver cirrhosis (LC). Methods 62 patients with hepatitis B cirrhosis were enrolled in our hospital between March 2018 and September 2020, and were divided into observation (n=32) and control group (n=30) when CTA was underwent, with segmented injection or conventional injection of contrast medium, respectivley. The hepatic artery perfusion (HAP), hepatic portal perfusion (HPP), hepatic perfusion index (HPI) and arterial perfusion fraction (APF) were recorded. Results The imaging quality in observation was much more superior to that in the control (P<0.05); the CT value of hepatic vein [(138.6±13.4)HU vs. (125.5±11.8 )HU], of main portal vein[(218.8±41.3)HU vs. (176.9±35.8)HU],of right branch of portal vein[(204.6±31.5)HU vs. (163.3±28.7)HU] and of left branch of portal vein [(198.5±21.9)HU vs. (154.0±23.2)HU]were statistically significantly different between the two groups (P<0.05); the peak contrast media time of portal vein [(17.5±2.2)HU vs. (19.7±3.0)HU] and the peak time of liver parenchyma [(35.7±3.8)HU vs. (40.1±4.3)HU]were statistically significantly different between observation and control group (P<0.05); the HAP[(16.3±4.8) ml/min/100ml vs. (15.8±5.2) ml/min/100ml], HPP [(18.9±5.7)ml/min/100ml vs. (17.5±6.4)ml/min/100ml], HPI[(40.6±10.1)% vs. (42.2±9.6)%]and APF [(31.2±8.3)% vs. (30.9±7.5)%] in the two groups were not statistically significantly different (P>0.05). Conclusion The segmented injection of contrast medium is superior to conventional injection when CTA is done, which might give us a high-quality imaging and help us make an appropriate diagnosis.

Key words: Liver cirrhosis, CT angiography, Segmented injection of contrast agents, Hepatic venography, Diagnosis

Xing Li, Du Qianying, Jiang Yanli, et al. Impact of segmented injection of contrast agent on hepatic vein imaging by CT angiography in patients with hepatitis B cirrhosis[J]. Journal of Practical Hepatology, 2021, 24(6): 871-874.

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Impact of segmented injection of contrast agent on hepatic vein imaging by CT angiography in patients with hepatitis B cirrhosis

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