血吸虫病性肝硬化患者腹部CT表现和CT定量参数特征观察*

doi:10.3969/j.issn.1672-5069.2021.05.010

Abstract

Abstract: Objective The purpose of this study was to investigate the abdominal computed tomography (CT) manifestations and CT quantitative parameters in patients with schistosomiasis liver cirrhosis (SLC). Methods A total of 72 patients with SLC and 25 healthy volunteers were enrolled in this study between May 2018 and May 2020. The patients with SLC included Child-Pugh class A in 26, Child-Pugh class B in 21, and Child-Pugh class C in 25. All the individuals underwent CT enhanced scan, and the blood volume (BV), blood flow (BF), mean transit time (MTT) , hepatic arterial fraction (HAF) and hepatic artery perfusion (HAP) were recorded. The laboratory indicators, such as total serum bilirubin, albumin, international standardized ratio of prothrombin time, white blood cell counts and platelet counts were detected. Results TheCT examination in 72 patients with SLC showed abnormal ratio of liver lobes, irregular contour and widening of liver fissure, a map-like, diffuse decrease of liver parenchyma density, high density schistosomia-like calcified nodules and portal vein dilatation in liver, portal vein and mesenteric vein, and the blood analysis demonstrated the injured liver function tests and hypersplenism; in healthy subjects,the abdominal CT perfusion parameters, e.g. the BV, BF, MTT, HAF and HAP levels were (47.3±8.2) ml/100g, (211.9±42.1) ml/min/100g, (12.9±3.1) s, (0.2±0.0) and (16.3±7.9) ml/min/100g, respectively, those in patients with SLC of Child-Pugh class A were (40.8±7.6) ml/100g, (183.1±37.2) ml/min/100g, (15.8±3.7) s, (0.3±0.0) and (19.1±8.8) ml/min/100g, in patients with Child-Pugh class B were (35.5±6.9) ml/100g, (124.7±33.2) ml/min/100g, (19.2±4.5) s, (0.3±0.0) and (24.5±9.9) ml/min/100g, and in patients with Child-Pugh class C were (24.8±8.4) ml/100g, (115.5±28.1) ml/min/100g, (24.6±5.5) s, (0.4±0.1) and (33.5±12.5) ml/min/100g, respectively, significantly different among them (P＜0.05). Conclusion The CT examination of liver in patients with SLC could show the morphological changes, and the CT perfusion parameters obtained might help evaluate the severity of liver injuries.

Key words: Liver cirrhosis, Schistosomiasis japonica, 64-slice spiral CT scan, Perfusion imaging

Ye Li, Wu Chenying, Song bin. Abdominal CT manifestations and CT quantitative parameters in patients with schistosomiasis cirrhosis[J]. Journal of Practical Hepatology, 2021, 24(5): 645-648.

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Abdominal CT manifestations and CT quantitative parameters in patients with schistosomiasis cirrhosis

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