采用实时三维超声和斑点追踪技术评价非酒精性脂肪性肝病肝硬化患者右心功能*

doi:10.3969/j.issn.1672-5069.2019.02.023

Abstract

Abstract: Objective To evaluate right atrial and ventricular functions in patients with nonalcoholic fatty liver disease （NAFLD） -induced liver cirrhosis （LC） by real-time three-dimensional echocardiography （RT-3DE） and speckle tracking imaging （2 D-STI）. Methods 70 patients （compensated in 35 and decompensated in 35） with NAFLD-induced LC and 35 healthy persons were recruited in our hospital between February 2015 and November 2016. The RAVI,LAD,RVIDd,RVIDs,IVS and LVPW were obtained by RT-3DE,and the RVFAC was calculated. The ETV and e'TV were measured and the ratio of ETV/e'TV was calculated. The TAPSE was obtained by M mode echocardiography. The MSs,MSe,MSa,MSRs,MSRe and MSRa were also measured by 2D-STI. Results The LAD,LVPW and ETV/e'TV in patients with compensated cirrhosis decreased as compared to those in healthy persons（P<0.05）;the RVIDs,IVS,LVPW and ETV/e'TV in patients with compensated cirrhosis decreased as compared to those in patients with decompensated cirrhosis（P<0.05）;the RAV max,RAV min,RAV pre,RAVIa and RAVIt in patients with liver cirrhosis significantly increased,while the RAVIp decreased as compared to those in control （P<0.05）;the RAV max,RAV min,RAV pre,RAVIa and RAVIt in patients with compensated cirrhosis significantly decreased,while the RAVIp increased as compared to those in patients with decompensated cirrhosis（P<0.05）;the MSe,MSRs and MSRa in patients with liver cirrhosis significantly increased,while the MSRe and MSa decreased as compared to those in control（P<0.05）;the MSs,MSe,MSRs,MSRe and MSRa in patients with compensated cirrhosis significantly increased,while the MSa decreased in patients with decompensated cirrhosis（P<0.05）. Conclusion The application of RT-3DE and 2D-STI in evaluating right atrial and ventricular functions in patients with NAFLD-induced LC might be helpful for clinicians to early predict the cardiac deficiency,which needs further investigations.

Key words: Liver cirrhosis, Nonalcoholic fatty liver disease, Real-time three-dimensional echocardiography, Speckle tracking imaging, Cardiac functions

Huo Huiqin, Gong Xiaohong, Li Zhenghong. Assessment of right atrial and ventricular functions in patients with nonalcoholic fatty liver disease-induced liver cirrhosis by real-time three-dimensional echocardiography and speckle tracking imaging[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2019, 22(2): 244-247.

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Assessment of right atrial and ventricular functions in patients with nonalcoholic fatty liver disease-induced liver cirrhosis by real-time three-dimensional echocardiography and speckle tracking imaging

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