肠道菌群对终末期肝病患者营养和代谢的作用

doi:10.3969/j.issn.1672-5069.2017.05.001

Abstract

Yao Jia，Yuan Lili，Duan Zhongping.. Contributions of intestinal bacteria to nutrition and metabolism in patients with end-stage liver disease[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2017, 20(5): 513-515.

[1] Clarke G，Stilling RM，Kennedy PJ，et al. Minireview:Gut microbiota:the neglected endocrine organ. Mol Endocrinol，2014，28:1221-1238.
[2] Flint HJ，Scott KP，Duncan SH，et al. Microbial degradation of complex carbohydrates in the gut. Gut Microbes，2012，3:289-306.
[3] Zhang J，Guo Z，Xue Z，et al. A phylo-functional core of gut microbiota in healthy young Chinese cohorts across lifestyles，geography and ethnicities. ISME J，2015，9:1979-1990.
[4] Xu J，Bjursell MK，Himrod J，et al. A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science，2003，299:2074-2076.
[5] Sun P，Wang JQ，Deng LF. Effects of Bacillus subtilis natto on milk production，rumen fermentation and ruminal microbiome of dairy cows. Animal，2013，7:216-222.
[6] Metges CC. Contribution of microbial amino acids to amino acid homeostasis of the host. J Nutr，2000，130:1857S-1864S.
[7] Raj T，Dileep U，Vaz M，et al. Intestinal microbial contribution to metabolic leucine input in adult men. J Nutr，2008，138:2217-2221.
[8] Backhed F，Ding H，Wang T，et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A，2004，101:15718-15723.
[9] Backhed F，Crawford PA. Coordinated regulation of the metabolome and lipidome at the host-microbial interface. Biochim Biophys Acta， 2010，1801:240-245.
[10] Ley RE，Turnbaugh PJ，Klein S，et al. Microbial ecology:human gut microbes associated with obesity. Nature，2006，444:1022-1023.
[11] Rosenbaum M，Knight R，Leibel RL. The gut microbiota in human energy homeostasis and obesity. Trends Endocrinol Metab，2015，26:493-501.
[12] Crawford PA，Crowley JR，Sambandam N，et al. Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation. Proc Natl Acad Sci U S A，2009，106:11276-11281.
[13] Kohl KD，Amaya J，Passement CA，et al. Unique and shared responses of the gut microbiota to prolonged fasting:a comparative study across five classes of vertebrate hosts. FEMS Microbiol Ecol，2014，90:883-894.
[14] Maharshi S，Sharma BC，Srivastava S. Malnutrition in cirrhosis increases morbidity and mortality. J Gastroenterol Hepatol，2015，30:1507-1513.
[15] Gomez-Hurtado I，Such J，Sanz Y，et al. Gut microbiota-related complications in cirrhosis. World J Gastroenterol，2014，20:15624-15631.
[16] Chen Y，Guo J，Qian G，et al. Gut dysbiosis in acute-on-chronic liver failure and its predictive value for mortality. J Gastroenterol Hepatol，2015，30:1429-1437.
[17] Chen Y，Yang F，Lu H，et al. Characterization of fecal microbial communities in patients with liver cirrhosis. Hepatology，2011，54:562-572.
[18] Chen Y，Qin N，Guo J，et al. Functional gene arrays-based analysis of fecal microbiomes in patients with liver cirrhosis. BMC Genomics，2014，15:753.
[19] Wiest R，Lawson M，Geuking M. Pathological bacterial translocation in liver cirrhosis. J Hepatol，2014，60:197-209.
[20] Yao J，Chang L，Yuan L， et al. Nutrition status and small intestinal bacterial overgrowth in patients with virus-related cirrhosis. Asia Pac J Clin Nutr，2016，25:283-291.
[21] Bures J，Cyrany J，Kohoutova D，et al. Small intestinal bacterial overgrowth syndrome. World J Gastroenterol，2010，16:2978-2990.
[22] Norman K，Pirlich M，Schulzke JD，et al. Increased intestinal permeability in malnourished patients with liver cirrhosis. Eur J Clin Nutr，2012，66:1116-1119.
[23] Wan X，Bi J，Gao X，et al. Partial enteral nutrition preserves elements of gut barrier function，including innate immunity，intestinal alkaline phosphatase（IAP） level，and intestinal microbiota in mice. Nutrients，2015，7:6294-6312.
[24] Ralls MW，Demehri FR，Feng Y，et al. Enteral nutrient deprivation in patients leads to a loss of intestinal epithelial barrier function. Surgery，2015，157:732-742.
[25] Reiberger T，Ferlitsch A，Payer BA，et al. Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis. J Hepatol，2013，58:911-921.
[26] Bajaj JS，Heuman DM，Sanyal AJ，et al. Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy. PLoS One，2013，8:e60042.
[27] Ren ZG，Liu H，Jiang JW，et al. Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation. Hepatobiliary Pancreat Dis Int，2011，10:489-496.
[28]Kao D，Roach B，Park H，et al. Fecal microbiota transplantation in the management of hepatic encephalopathy. Hepatology，2016，63:339-340.

Contributions of intestinal bacteria to nutrition and metabolism in patients with end-stage liver disease

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