Abstract: Objective To analyze the risk factors for acute myocardial damage in patients with hepatitis B cirrhosis complicated by esophageal and gastric variceal bleeding. Methods Clinical data of 152 patients with hepatitis B cirrhosis and esophageal and gastric variceal bleeding between July 2010 and December 2015 were retrospectively analyzed. Acute myocardial damage were recorded. Independent risk factors were obtained by multivariate Logistic regression analysis. Results There were 65 patients （42.76%） having acute myocardial damage among the 152 patients with hepatitis B liver cirrhosis complicated by esophageal and gastric variceal bleeding;Univariate analysis showed that patients who were younger than 52 years,whose body mass index （BMI） less than 26 kg/m²,had liver function of Child-Pugh class A,had no hypertension,had no diabetes,had no history of heart disease,whose serum creatinine（sCr） levels being lower than 81 μmol/L and C-reactive protein （CRP） levels being lower than 16 mg/L,and blood potassium being lower than 3.7 mmol/L had lower incidence of acute myocardial damage as compared to those in the opposite ones（P<0.05 for all）;the multivariate logistic regression analysis revealed that age,liver function class,diabetes mellitus,heart disease history,sCr level,serum potassium and CRP levels were the independent risk factors for acute myocardial damage in patients with hepatitis B cirrhosis and esophageal and gastric variceal bleeding. Conclusion The incidence of acute myocardial damage in patients with hepatitis B cirrhosis and esophageal and gastric variceal bleeding is high,which must be taken into consideration in clinical practice.

Key words: Liver cirrhosis, Esophageal and gastric variceal bleeding, Acute myocardial damage, Risk factor