Journal of Practical Hepatology ›› 2025, Vol. 28 ›› Issue (6): 957-960.doi: 10.3969/j.issn.1672-5069.2025.06.040

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Intervention for sarcopenia in patients with chronic liver diseases

Zhang Siqi, Kong Ming, Duan Zhongping   

  1. Section 4, Liver Disease Study Center, Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, You’an Hospital, Capital Medical University, Beijing 100069, China
  • Received:2024-10-14 Online:2025-11-10 Published:2025-11-13

Abstract: Sarcopenia is a systemic entity in which muscle mass and strength progressively decline. Sarcopenia is associated with poor outcomes and prognosis in patients with chronic liver disease, particularly in those at the end-stage. On the basis of traditional nutritional supplementation and exercise intervention, the existing intervention are extending more to target therapy for signaling pathways. In this review, we summarized the progress of intervention for sarcopenia in patients with chronic liver disease, in order to provide more references for the clinical management of sarcopenia.

Key words: Chronic liver disease, Sarcopenia, Intervention