Journal of Practical Hepatology ›› 2021, Vol. 24 ›› Issue (4): 603-606.doi: 10.3969/j.issn.1672-5069.2021.04.038

Previous Articles     Next Articles

Simvastatin: a newface for treatment of patients with chronic liver disease

Bi Zaihong, Hanbai Yila, Wang Bingyuan   

  1. Department of Alcohol-related Liver Diseases, Infectious Disease Hospital, Tongliao 028000, Inner Mongolia Autonomous Region, China
  • Received:2020-12-29 Published:2021-07-13

Abstract: Objective Besides its lipid-lowering function, the simvastatin also exhibits multiple pleiotropic effects, such as antioxidative, antiproliferative and antiinflammatory properties, as well as the capacity to improve endothelial function and to stimulate neoangiogenesis. It rarely lead to apparent clinical acute liver injury, and might be a new choice for the treatment of patients with chronic liver diseases. In this article, we briefly introduce the basic and clinical researches of simvastatin in the treatment of patients with chronic liver diseases.

Key words: Chronic liver diseases, Simvastatin, Therapy