双源CT双能量TNC技术图像质量与诊断肝细胞癌效能分析*

doi:10.3969/j.issn.1672-5069.2024.06.029

Abstract

Abstract: Objective The purpose of this study was to investigate the image quality and diagnostic efficacy of dual-source CT dual-energy true non-contrast enhanced (TNC) technique in patients with hepatocellular carcinoma(HCC). Methods 85 patients with intrahepatic space-occupying lesions were admitted to our hospital between January 2020 and January 2023, and all underwent dual-source CT dual-energy enhanced scanning to obtain the TNC and virtual non-contrast enhanced (VNC) imaging, signal to noise ratio (SNR) and contrast noise ratio (CNR). The imaging quality was subjectively evaluated by five scores. Results Out of the 85 patients with intrahepatic space-occupying lesions, the histopathological examination diagnose HCC in 48 cases, focal nodular hyperplasia (FNH) in 23 cases and hepatic hemangioma (HH) in 14 cases; the standard deviation (SD) of CT value of the hepatic lesion/right erector spinalis muscle at same level and the radiation dose in TNC-showed HCC foci were(7.9±1.8)HU and (5.9±0.6)mSv, both significantly greater than [(6.7±1.3)HU and (3.6±0.7)mSv, respectively, P<0.05] showed by VNC, while the SNR was (5.4±1.6), much smaller than [(6.5±1.7), P<0.05] showed by VNC; all the SD and the radiation dose in HCC, FNH and HH foci by TNC imaging were significantly greater than by VNC imaging(P＜0.05), while the SNR was much lower than by VNC imaging (P＜0.05); the CT values of HCC lesions by both TNC and VNC were greater than in FNH or HH foci (P＜0.05); the subjective image quality score of HCC lesions by TNC was superior to by VNC imaging (P＜0.05); the sensitivity, specificity and accuracy of TNC imaging in diagnosing HCC were 89.6%, 91.9% and 90.6%, much superior to 72.9%, 78.4% and 75.3%, respectively (P＜0.05) by VNC imaging. Conclusion In dual-source CT dual-energy enhanced scan, although TNC images have higher radiation dose, the quality of TNC images is higher than that of VNC images, and the accuracy of TNC images in diagnosing hepatocellular carcinoma is higher, which has certain guiding value for clinical diagnosis of hepatocellular carcinoma.

Key words: Hepatocellular carcinoma, Dual-source CT dual-energy, True non-contrast enhanced, Virtual non-contrast enhanced, Image quality, Diagnosis

Yang Jiaxin, Yang Zijun, Chen Wei. Image quality and diagnostic efficacy of dual-source CT dual-energy TNC technique in patients with hepatocellular carcinoma[J]. Journal of Practical Hepatology, 2024, 27(6): 915-918.

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Image quality and diagnostic efficacy of dual-source CT dual-energy TNC technique in patients with hepatocellular carcinoma

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