Abstract: Objective The aim of this study was to summarize the clinical feature, electrocardiogram manifestations and related risk factors in patients with cirrhotic cardiomyopathy (CCM). Methods 89 patients with liver cirrhosis were enrolled in our hospital between May 2020 and May 2023, and all underwent digital electrocardiograph (EKG). The echocardiogram was conducted to record the left atrial diameter (LAD), left ventricular end-diastolic diameter (LVDd), left ventricular end-systolic diameter (LVDs), diastolic interventricular septal thickness (IVSD), left ventricular ejection fraction (LVEF), and mitral valve early diastolic peak velocity/late peak velocity (E/A) ratio. The multivariate Logistic regression analysis was applied to predict the risk factors of CCM occurrence. Results Out the 89 patients with liver cirrhosis, 21 cases (23.6%) were found complicated with CCM; the LAD and IVSD in patients with CCM were (38.7±4.4) mm and (11.8±1.7)mm, significantly greater than [(35.3±3.9)mm and (10.0±1.5)mm, respectively, P<0.05], while the E/A ratio was (0.8±0.1), much less than [(1.3±0.2, P<0.05] in liver cirrhosis patients without CCM; the percentages of prolonged Q-T intervals, ST-T changes and limb lead low voltage in patients with CCM were 76.2%, 66.7% and 28.6%, much higher than 35.3%, 30.9% and 5.9%(P<0.05) in liver cirrhosis patients without CCM; there were significant differences as respect to the ages, Child-Pugh class C, diameters of portal vain, serum creatinine (sCr) levels, prothrombin times and hemoglobin (Hb) levels between the two groups (P<0.05); the multivariate Logistic regression analysis showed that the age (OR=1.54, 95%CI=1.09-2.17), the liver function Child-Pugh class C (OR=2.78, 95%CI=1.18-6.56) and hypohemoglobinemia (OR=2.58, 95%CI=1.29-5.14) were the independent risk factors of CCM occurrence in patients with liver cirrhosis. Conclusion Because of the hyperkinetic circulatory state, the patients with decompensated liver cirrhosis might have the complications of CCM, especially in elderly patients with deteriorated liver functions and hypohemoglobinemia, and the clinicians should pay more attention to them.

Key words: Cirrhotic cardiomyopathy, Echocardiogram, Electrocardiogram, Risk factors