Abstract: Objective The aim of this study was to investigate the diagnostic performance of multi-slice computed tomography (CT) and magnetic resonance imaging (MRI) dynamic enhancement in patients with hypervascular intrahepatic cholangiocarcinoma (ICC). Methods 66 patients with ICC were admitted to our hospital between August 2019 and June 2021, and all patients underwent multi-slice spiral CT and MRI dynamic enhanced examinations, and radical resection of tumor. The CT and MRI imaging characteristics of ICC were analyzed and the histopathological examination was performed. The area under the receiver operating characteristic curve (AUC) was applied to evaluate the diagnostic efficacy. Results 26 cases with hypervascularity and 40 cases with hypovascularity of tumors were diagnosed by post-operational pathology out of our 66 patients with ICC; the multi-slice spiral CT scans showed tumor lesions in the arterial phase, with continuous enhancement in the venous phase and delayed phase in 21 patients with hypervascular ICC, while showed no obvious enhancement in the arterial phase, portal venous phase and delayed phase in 5 patients; the dynamic contrast-enhanced MRI revealed tumor lesions with heterogeneous enhancement in the arterial phase, and heterogeneous enhancement in the venous phase and delayed phase in 24 patients with hypervascular ICC, and did not appear tumorous imaging appearance in the arterial phase and in portal venous phase, and significant homogeneous enhancement in the delayed phase in 2 patients; the ROC analysis showed that the AUC was 0.869 (95%CI:0.77-0.94), with the sensitivity (Se) and specificity (Sp) of 76.9%(95%CI:59.56-90.56) and 95.0%(95%CI:83.96-99.24)by CT scan, while the AUC was 0.872(95%CI:0.78-0.94), with the Se and Sp of 88.5%(95%CI:70.07～95.92) and 85.0%(95%CI:73.05-94.58) by MR scan. Conclusions The hypervascular ICC has certain features on multi-slice spiral CT and MRI dynamic contrast-enhanced scans, which might be helpful for the evaluation of tumor with hypervascularity, and making appropriate measurement.

Key words: Intrahepatic cholangiocarcinoma, Multi-slice computed tomography, Magnetic resonance imaging, Imaging features, Diagnosis