[1] STEINMAN RM. Dendritic cells:Understanding immunogenicity[J]. Eur J Immunol,2007,37:S53-60. [2] LIU YJ. Dendritic cells subsets and lineages and their functions in innateand adaptive immunity[J]. Cell,2001,106:259-262. [3] AMSEN D,BLANDER JM,LEE GR,et al. Instruction of distinct CD4T helper cell fates by different notch ligands on antigen-presenting cells[J]. Cell,2004,117(4):515-526. [4] 龚非力. 医学免疫学[M]. 3版.北京:科学出版社,2009:111. [5] THOMSON AW,DRAKES ML,ZAHORCHAK AF,et al. Hepatic dendritic cells:immunobiology and role in liver transplantation[J]. Leukoc Biol,1999,66:322-330. [6] MIRIAN M,MARKUS G. Dendritic cell homeostasis[J]. Blood, 2009,113:3418-3427. [7] O’CONNELL PJ,MPRELLI AE,LOGAR AJ,et al. Phenotypic and fuctionnal characterization of mouse hepatic CD8 alpha+ lymphoid-related dendritic cells[J]. Immunology,2000,165:795-803 [8] LIAN ZX,OKKADA T,HE XS,et al. Heterogeneity of dendritic cells in the mouse liver:identification and characterization of four distinct populations[J]. Immunology,2003,170:2323-2330. [9] JOMANTAITE I,DIKOPOULOS N,KROGER A,et al. Hepatic dendritic cell subsets in the mouse[J]. Eer J Immunol,2004,34:355-365. [10] PILLARISETTY VG,SHAH AB,MILLER G,et al. Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition[J]. Immunology,2004,172:1009-1017. [11] DUNN C,PEPPA D,KHANNA P,et al. Temporal analysis of early immune responses in patients with acute hepatitis B virus infection[J]. Gastroenterology,2009,137:1289-1300. [12] MORETTA L,FERLAZZO G,BOTTINO C,et al. Effector and regulatory events during natural killer-dendritic cell interactions[J]. Immunol Rev,2006,214:219-228. [13] RUPRECHT CR,LANZAVECCHIA A. Toll-like receptor stimulation as a third signal required for activation of human naive B cells[J]. Eur J Immunol,2006,36(4):810-816. [14] ZAMMIT DJ,LEFRANCOIS L. Dendritic cell-T cell interactions in the generation and maintenance of CD8 T cell memory[J]. Microbes Infect,2006,8(4):1108-1115. [15] GANEM D,PRINCE AM. Hepatitis B virus infection natural history and clinical consequences[J]. N Engl J Med,004,350(11):1118-1129. [16] ZHANG Z,CHEN D,YAO J,et al. Increased infiltration of intrahepatic DC subsets closely correlate with viral control and liver injury in immune active pediatric patients with chronic hepatitis B[J]. Clin Immunol,2007,122(2):173-180. [17] OP DEN BROUW ML,BINDA RS,VAN ROOSMALEN MH,et al. Hepatitis B virus surface antigen impairs myeloid dendritic cell function:a possible immune escape mechanism of hepatitis B virus[J]. Immunology,2009,126(2):280-289. [18] ARIMA S,AKBAR SM,MICHITAKA K,et a1. Impaired function of antigen-presenting dendritic cells in patients with chronic hepatitis B:localization of HBV DNA and HBV RNA in blood DC by in situ hybridization[J]. Int J Mol Med,2003,11(2):169-174. [19] VANDER MOLEN RG,SPRENGERS D,BINDA RS,et al. Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B[J]. Hepatology,2004,40(3):738-746. [20] OP DEN BROUW ML,BINDA RS,VAN ROOSMALEN MH,et al. Hepatitis B virus surface antigen impairs myeloid dendritic cell function:a possible immune escape mechanism of hepatitis B virus[J]. Immunology,2008,126:280-289. [21] WOLTMAN AM,OP DEN BROUW ML,BIESTA PJ,et al. Hepatitis B virus lacks immune activating capacity,but actively inhibits plasmacytoid dendritic cell function[J]. PLoS ONE,2011,6(1):e15324.doi:10.1371/journal.pone.0015324 [22] WANG FS,XING LH,LIU MX,et al. Dysfunction of peripheral blood den-dritic cells from patientswith chronic hepatitis B virus infections[J]. World J Gastroenterol,2001,7:537-541. [23] ZHENG BJ,ZHOU J,QU D,et al. Selective functional deficit in dendritic cell-T cell interaction is a crucial mechanism in chronic hepatitis B virus infection[J]. J Viral Hepat,2004,11(3):217-224. [24] TOSI D,VALENTI R,COVA A,et al. Role of cross talk between IFN-alpha induced monocyte-derived dendritic cells and NK cells in priming CD8 positive T cell responses against human tumor[J]. Immunology,2004,112:28-37. [25] FONTENEAU JF,LARSSON M,BEIGNON AS,et al. Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells[J]. J Virol,2004,78:5223-5232. [26] LUFT T,LUETJENS P. IFN-αenhances CD40 ligand-mediated activation of immature monocyte derived dendritic cell[J]. Int Immunol,2002,14:367-380. [27] 朱传武,钱峰,王海燕,等. 干扰素抗病毒应答与慢性乙型肝炎患者外周血树突状细胞功能的关系[J]. 抗感染病学,2004,1(2):60-63. [28] BONI C,PENNA A,OGG GS,et al. Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B:New perspectives for immunotherapy[J]. Hepatology,2001,33:963-971. [29] 李捍卫,朱慧芬,王福生,等. 慢性乙型肝炎患者抗病毒治疗前后外周血树突状细胞和淋巴细胞亚群的变化及意义[J]. 中华实验和临床病毒学杂志,2006,3(20):43-46. [30] COOKSLEY H,CHOKSHI S,MAAYAN Y,et al. Hepatitis B virus e-antigen loss during adefovir dipivoxil therapy is associated with enhanced virus-specific CD4+ T-cell reactivity[J]. Antimicrob Agents Chemother,2008,52(1):312-320. [31] 卢高峰,唐芙爱,郑鹏远,等. 恩替卡韦对慢性乙型肝炎患者树突状细胞功能的体外影响[J]. 世界华人消化杂志,2007,11:1292-1296. [32] 朱传武,王海燕,钱峰,等. 干扰素A治疗对慢性乙型肝炎患者外周血树突状细胞抗原提呈作用的影响[J]. 中华医学杂志,2004,84(1):14-17. [33] AKBAR SM,FURUKAWA S,HASEBE A,et al. Production and efficacy of a dendritic cell-based therapeutic vaccine for murine chronic hepatitis B virus carrierer[J]. Int J Mol Med,2004,14(2):295-299. [34] DING CL,YAO K,ZHANG TT,et al. Generation of cytotoxic T cell against HBcAg using retrovirally transduced dendritic cells[J]. World J Gastroenterol,2003,9(7):1512-1515. [35] 李用国,陈敏,张大志,等. 自体树突状细胞疫苗治疗慢性乙型肝炎的临床研究[J]. 中华肝脏病杂志,2003,11(4):206-208. [36] AKABAR SM,ABE M,MASUMOTO T,et al. Mechanism of action of vaccine therapy in murine hepatitis B virus carriers:vaccine-induced activation of antigen presenting dendritic cells[J]. J Hepatol,1999,30(5):755-764. [37] YOU Z,HUANG X,HESTER J,et al. Targeting dendritic cells to enhance DNA vaccine potency[J]. Cancer Res,2001,61(9):3704-3711. [38] GREDLER V,EBNER S,SCHANDA K,et al. Impact of human myelin on the maturation and function of human monocyte-derived dendritic cells[J]. Clin Immunol,2010,134:296-304. [39] STAEINMAN RM,BANCHEREAU J. Taking dendritictic cells into medicine[J]. nature,2007,449:419-426. |