慢性乙型肝炎患者外周血NK细胞和T淋巴细胞计数变化及其临床意义

doi:10.3969/j.issn.1672-5069.2010.03.007

Abstract

Abstract: Objective To investigate the counts of natural killer cells and T lymphocytes in patients with chronic hepatitis B. Methods The CD3⁺T cells,CD3⁺CD4⁺T cells,CD3⁺CD8⁺T cells and CD3^-CD16⁺CD56⁺NK cells in peripheral blood were counted by FCM. Results The T lymphocytes and NK cells decreased in 56 patients with hepatitis B-related hepatic failure;the CD3^-CD16⁺CD56⁺ natural killer cells in 49 patients with chronic hepatitis B increased as compared to in 41 chronic hepatitis B viral carriers. Conclusions The T lymphocytes and NK cells in patients with hepatic failure decreased while T lymphocytes in patients with chronic hepatitis B with HbeAg positive increased.

Key words: Chronic hepatitis B, Natural killer cells, T lymphocytes

QIU Jie, LONG Qiqiang, FENG Yanhong, et al.. Investigation of T lymphocytes and natural killer cells in patients with chronic hepatitis B[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2010, 13(3): 178-179.

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Investigation of T lymphocytes and natural killer cells in patients with chronic hepatitis B

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