[1] 中华医学会肝病学分会,感染病学分会. 慢性乙型肝炎防治指南[J]. 实用肝脏病杂志,2006,9(1):8-18. [2] CHENNA H,ILOEJE,HWAI-I YANG,et al. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load[J]. Gastroenterology,2006,130:678-686. [3] 陆伦根,曾民德. 肝纤维化非创伤性诊断研究进展[J]. 中华医学杂志,2005,85:1078-1080. [4] 赵连荣,许德军,陆忠华,等. 综合预测模型FibroTest对慢性乙型肝炎肝纤维化的诊断价值[J]. 中国实用内科杂志,2007,27(1):1274-1277. [5] WANG CC,LIM LY,DEUBNER H,et al. Factors predictive of significant hepatic fibrosis in adults with chronic hepatitis B and normal serum ALT[J]. J Clin Gastroenterol,2008,42(7):820-826. [6] AKUTA N,KUMADA H. Influence of hepatitis B virus genotypes on the response to antiviral therapies[J]. J Antimicrob Chemother,2005,55(2):139-142. [7] ALAZAWI W,FOSTER GR. Advances in the diagnosis and treatment of hepatitis B[J]. Curr Opin Infect Dis,2008,21:508-515. [8] SANDRIN L,FOURQUET B,HASQUENOPH JM,et al. Transient elastography:a new noninvasive method for assessment of hepaticfibrosis[J]. Ultrasound Med Biol,2003,29:1705-1713. [9] NGUYEN-KHAC E,CAPRON D. Noninvasive diagnosis of liver fibrosis by ultrasonic transient elastography[J]. Eur J Gastroenterol Hepatol,2006,18(12):1321-1325. [10] YIN M,TALWALKAR JA,GLASER KJ,et al. Assessment of hepatic fbrosis with magnetic resonance elastography[J]. Clin Gastroenterol Hepatol,2007,5:1207-1213. [11] 中国中西医结合学会肝病专业委员会. 肝纤维化中西医结合诊疗指南[J]. 中华肝脏病杂志,2004,4(6):551-554. [12] LIN S,YU M,LEE C,et al. Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma[J]. J Hepatol,2007,46:45-52. [13] PAPATHEODORIDIS GV,PETRAKI K,CHOLONGITAS E,et al. Impact of interferon-alpha therapy on liver fibrosis progression in patients with HBeAg-negative chronic hepatitis B[J]. J Viral Hepat,2005,12:199-206. [14] VAN ZONNEVELD M,ZONDERVAN PE,CAKALOGLU Y,et al. Peg-interferon improves liver histology in patients with HBeAg-positive chronic hepatitis B:no additional benefit of combination with lamivudine[J]. Liver Int,2006,26(4):399-405. [15] ERHARDT A,BLONDIN D,HAUCK K,et al. Response to interferon alfa is hepatitis B virus genotype dependent:genotype A is more sensitive to interferon than genotype D[J]. Gut,2005,54(7):1009-1013. [16] LAU DT,KHOKHAR F,DOO E,et al. Long-term therapy of chronic hepatitis B with lamivudine[J]. Hepatology,2000,32:828-834. [17] NISHIDA T,KOBASHI H,FUJIOKA S,et al. A prospective and comparative cohort study on efficacy and drug resistance during long-term lamivudine treatment for various stages of chronic hepatitis B and cirrhosis[J]. J Gastroenterol Hepatol,2008,23:794-803. [18] YUEN MF,CHOW DH,TSUI K,et al. Liver histology of asian patients with chronic hepatitis B on prolonged lamivudine therapy[J]. Aliment Pharmacol Ther,2005,21(7):841-849. [19] P MARCELLIN,EJ HEATHCOTE,M BUTI,et al. Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B[J]. N Engl J Med,2008,359(23):2442-2455. [20] MANOLAKOPOULOS S,BETHANIS S,KOUTSOUNAS S,et al. Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine[J]. Aliment Pharmacol Ther,2008,27:266-273. [21] MARCELLIN P,CHANG TT,LIM SG,et al. Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B[J]. Hepatology,2008,48(3):750-758. [22] KOBASHI H,TAKAGUCHI K,IKEDA H,et al. Efficacy and safety of entecavir in nucleoside-naive,chronic hepatitis B patients:Phase II clinical study in Japan[J]. J Gastroenterol Hepatol,2009,24:255-261. [23] LAI CL,GANE E,LIAW Y,et al. Telbivudine versus lamivudine in patients with chronic hepatitis B[J]. N Engl J Med,2007,357:2576-2588. [24] NIDHI A,SINGH,NANCY R. Management of hepatitis B virus[J]. J Antimicrob Chemother,2008,62:224-228. [25] BATALLER R,BRENNER DA. Liver fibrosis[J]. J Clin Invest,2005,115:209-218. [26] CUI X,SAKATA R,UENO T,et al. Inhibitory effect of a soluble transforming growth factor-h type II receptor on the activation of rat hepatic stellate cells in primary culture[J]. J Hepatol,2003,39:731-737. [27] MURATA S,HASHIMOTO I,NAKANO Y. Single Administration of thrombopoietin prevents progression of liver fibrosis and promotes liver regeneration after partial hepatectomy in cirrhotic rats[J]. Ann Surg,2008,248(5):821-828. [28] WANG LS,CHEN YW,LI DG,et al. Arg-gly-asp-mannose-6-phosphate inhibits activation and proliferation of hepatic stellate cells in vitro[J]. World J Gastroenterol,2006,12:1303-1307. |