实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (4): 268-269.doi: 10.3969/j.issn.1672-5069.2011.04.010

• 论著 • 上一篇    下一篇

慢性乙型重型肝炎近期预后的指标探讨

乔飞,盛云峰,徐静,张馨,马丽佳,隋云华,何长伦,高蕾,汪茂荣   

  1. 210002 南京市 解放军第81医院全军肝病中心
  • 收稿日期:2011-02-24 出版日期:2011-08-10 发布日期:2016-04-15
  • 通讯作者: 汪茂荣,E-mail: maorongwang@gmail.com
  • 作者简介:乔飞 男,37岁,医学硕士,副主任医师。E-mail:qf88888@yahoo.com.cn

Factors influencing the short-term prognosis of patients with chronic severe hepatitis B

QIAO Fei, SHENG Yunfeng,XU Jing,et al.   

  1. Institute of Liver Disease,the 81st Hospital of PLA,Nanjing 210002
  • Received:2011-02-24 Online:2011-08-10 Published:2016-04-15

摘要: 目的 回顾性分析影响慢性乙型重型肝炎(CHS)近期生存的相关因素。方法 对155例CSH患者的临床资料进行回顾性多因素回归分析。结果 本组患者3个月内生存60例(38.7%),死亡95例(61.3%);生存患者PTA(31.26±6.08%)、球蛋白(32.28±9.13g/l)明显高于死亡患者(26.11±9.76%和29.32±7.14g/l,P<0.01和P<0.05);生存患者TBIL(335.74±123.27μmol/L)、WBC(6.5±3.0×109/L)和中性粒细胞比值(64.42±14.59%)明显低于死亡患者(382.78±141.15μmol/L、8.8±5.4×109/L、71.63±11.37%,P<0.05、P<0.05、P<0.01);中性粒细胞比值、球蛋白和PTA与生存密切相关。结论 研究影响慢性乙型重型肝炎病情近期预后的因素有重要的意义。

关键词: 慢性乙型重型肝炎, 预后, 凝血酶原活动度

Abstract: Objective To retrospectively analyze the factors influencing the short-term prognosis of patients with chronic severe hepatitis B(CSH). Methods Clinical data of 155 patients with CSH were retrospectively analyzed. Results 60(38.7%)survived and 95(61.3%)died in this series;PTA(31.26±6.8%)and globulin(32.28±9.13g/l)in survivals were obviously higher than those in dead(26.11±9.76% and 29.32±7.14g/l,P<0.01,P<0.05);the TBIL(335.74±123.27μmol/L),WBC(6.5±3.0×109/L)and neutrophil ratio(64.42±14.59%)in survivals were obviously lower than in dead(382.78±141.15μmol/L,8.8±5.4×109/L and 71.63±11.37%,P<0.05,P<0.05,P<0.01);neutrophil ratio,globulin and PTA were strongly related to patients'prognosis. Conclusion It is important to predict the short-term prognosis of patients with CSH.

Key words: Chronic severe hepatitis B, Prognosis, PTA