脾脏硬度检测在慢性肝病无创诊断中的应用*

doi:10.3969/j.issn.1672-5069.2015.02.030

摘要/Abstract

摘要： 一直以来,慢性肝病都是广受关注的公共健康问题,它在全球范围内的发病率及致死率都很高。随着肝病迁延不愈,在慢性肝炎基础上出现不同程度的肝纤维化,甚至发展至肝硬化和肝癌。门静脉测压、胃镜筛查食管胃静脉曲张以及肝活检等有创检查需患者承担一定的风险,且技术要求较高,难以在临床推广使用。目前,越来越多的研究聚焦于无创诊断领域。随着肝病发展,肝硬度和脾硬度出现相应的变化,其检测也引起了广泛关注。

关键词: 慢性肝病, 脾脏, 弹性, 门脉高压

Abstract: Chronic liver diseases,having high morbidity and mortality,are important public-health problems worldwide. Chronic hepatitis may progress into advanced liver fibrosis,cirrhosis or even liver cancer. The correct evaluation of the severity of liver diseases is therefore necessary. However,the liver biopsy is invasive, and the measurement of hepatic venous pressure gradient is complicated. Recently,many studies suggest that non-invasive diagnostic techniques to measure the changes of liver and spleen stiffness are correlated with the severity and progression of liver diseases. This review mainly discuss the application of spleen stiffness measurement in non-invasive diagnosis of patients with chronic liver diseases.

Key words: Chronic liver diseases, Spleen, Stiffness, Portal hypertension

曾静, 范建高. 脾脏硬度检测在慢性肝病无创诊断中的应用^*[J]. 实用肝脏病杂志, 2015, 18(2): 209-212.

Zeng Jing, Fan Jiangao. Spleen stiffness measurement in non-invasive diagnosis of patients with chronic liver diseases[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2015, 18(2): 209-212.

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脾脏硬度检测在慢性肝病无创诊断中的应用^*

Spleen stiffness measurement in non-invasive diagnosis of patients with chronic liver diseases

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