[1] Nomura S,Ogami K,Kawamura K,et al.Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization. Exp Hematol,1997,25(7):565-572. [2] Stoffel R,Wiestner A,Skoda RC,Thrombopoietin in thrombocytopenic mice:evidence against regulation at the mRNA level and for a direct regulatory role of platelets. Blood,1996,87(2):567-573. [3] Desmond R,Townsley DM,Dumitriu B,et al.Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug. Blood,2014,123(12):1818-1825. [4] Majka M,Janowska-Wieczorek A,Ratajczak J,et al.Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. Blood,2000,96(13):4142-4151. [5] Li J,Xia Y,Kuter DJ.Interaction of thrombopoietin with the platelet c-mpl receptor in plasma:binding,internalization,stability and pharmacokinetics. Br J Haematol,1999. 106(2):345-356. [6] Fielder PJ,Gurney AL,Stefanich E,et al.Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets. Blood,1996,87(6):2154-2161. [7] Saur SJ,Sangkhae V,Geddis AE,et al.Ubiquitination and degradation of the thrombopoietin receptor c-Mpl. Blood,2010,115(6):1254-1263. [8] Kubota Y,Arai T,Tanaka T,et al.Thrombopoietin modulates platelet activation in vitro through protein-tyrosine phosphorylation. Stem Cells,1996,14(4): 439-444. [9] Cuong NT,Doi T,Matsushima-Nishiwaki R,et al. Thrombopoietin amplifies ADP-induced HSP27 phosphorylation in human platelets:importance of pre-treatment. Int J Mol Med,2013,31(6):1291-1297. [10] Zeldis JB,Mugishima H,Steinberg HN,et al.In vitro hepatitis B virus infection of human bone marrow cells. J Clin Invest,1986,78(2): 411-417. [11] El Barbary MA,Saad AE,Attia FM,et al.Thrombocytopenia in patients with chronic hepatitis C:a possible role of HCV on platelet progenitor cell maturation. Angiology,2010,61(3):304-313. [12] Garcia-Suarez J,Burgaleta C,Hernanz N,et al.HCV-associated thrombocytopenia:clinical characteristics and platelet response after recombinant alpha2b-interferon therapy. Br J Haematol,2000,110(1):98-103. [13] Joo EJ,Chang Y,Yeom JS,et al.Hepatitis B infection is associated with an increased incidence of thrombocytopenia in healthy adults without cirrhosis. J Viral Hepat,2017,24(3):253-258. [14] Weksler BB.The pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease. Aliment Pharmacol Ther,2007,26(Suppl 1):13-19. [15] Dai CY,Ho CK,Huang JF,et al.Hepatitis C virus viremia and low platelet count:a study in a hepatitis B & C endemic area in Taiwan. J Hepatol,2010,52(2):160-166. [16] Girard DE,Kumar KL,McAfee JH. Hematologic effects of acute and chronic alcohol abuse. Hematol Oncol Clin North Am,1987,1(2):321-334. [17] Emmons RV,Reid DM,Cohen RL,et al.Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. Blood,1996,87(10):4068-4071. [18] Temel T,Cansu DU,Temel HE,et al.Serum thrombopoietin levels and its relationship with thrombocytopenia in patients with cirrhosis. Hepat Mon,2014,14(5):e18556. [19] El-Sayed R,El-Ela MA,El-Raziky MS,et al.Relation of serum levels of thrombopoietin to thrombocytopenia in extrahepatic portal vein obstruction versus cirrhotic children. J Pediatr Hematol Oncol,2011,33(7):e267-270. [20] Peck-Radosavljevic M,Zacherl J,Meng YG,et al. Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver J Hepatol,1997,27(1):127-131. [21] Zhang W,Nardi MA,Borkowsky W,et al.Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia. Blood,2009,113(17):4086-4093. [22] Chiao EY,Engels EA,Kramer JR,et al.Risk of immune thrombocytopenic purpura and autoimmune hemolytic anemia among 120 908 US veterans with hepatitis C virus infection. Arch Intern Med,2009,169(4):357-363. [23] Gemery JM,Forauer AR,Silas AM,et al.Hypersplenism in liver disease and SLE revisited:current evidence supports an active rather than passive process. BMC Hematol,2016,16(1):3. [24] Jiang A,Zhang S,Li Z,et al.miR-615-3p promotes the phagocytic capacity of splenic macrophages by targeting ligand-dependent nuclear receptor corepressor in cirrhosis-related portal hypertension. 2011,236(6):672-680. [25] Shelat SG,Ai J,Zheng XL.Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays. Semin Thromb Hemost,2005,31(6):659-672. [26] Uemura M,Fujimura Y,Matsumoto M,et al.Comprehensive analysis of ADAMTS13 in patients with liver cirrhosis. Thromb Haemost,2008,99(6):1019-1029. [27] Uemura M,Fujimura Y,Ko S,et al.Pivotal role of ADAMTS13 function in liver diseases. Int J Hematol,2010,91(1):20-29. [28] Zander CB,Cao W,Zheng XL.ADAMTS13 and von Willebrand factor interactions. Curr Opin Hematol,2015,22(5):452-459. [29] Aster RH.Pooling of platelets in the spleen: role in the pathogenesis of“hypersplenic” thrombocytopenia. J Clin Invest,1966,45(5):645-657. [30] Shahab N,Evans ML.Images in clinical medicine. Platelet satellitism. N Engl J Med,1998,338(9):591. [31] Sultan S,Irfan SM.Platelet satellitism: a spurious cause of thrombocytopenia in chronic liver disease. Eur J Haematol,2015,94(1):90-91. [32] 潘圣红. 肝硬化并发假性血小板减少1例.临床合理用药杂志,2014,7(2):106. |