miRNAs在HBV感染及肝癌发病中的作用

doi:10.3969/j.issn.1672-5069.2016.03.035

摘要/Abstract

摘要： miRNAs是一类非编码的小RNA，对细胞增殖、分化、凋亡起着重要的作用。最重要的是它可以导致组织细胞发生癌变。肝癌是最常见的恶性肿瘤之一，HBV感染是导致肝癌发生的最为重要的危险因素，miRNAs在此过程中起到很重要的作用。本文将对miRNAs在HBV感染及在肝癌发病中扮演的角色做逐一阐述。

关键词: 肝细胞癌, 微小RNA, 乙型肝炎病毒

Abstract: MicroRNAs（miRNAs） are a kind of non-coding RNAs，which play an important role in cell proliferation，differentiation and apoptosis. Most importantly，miRNAs take part in carcinogenesis. HBV infection is the most important risk factor related to the occurrence of liver cancer and miRNAs are involved in this process.

Key words: Hepatocellular carcinoma, MicroRNAs, Hepatitis B virus

王毅，杨振华. miRNAs在HBV感染及肝癌发病中的作用[J]. 实用肝脏病杂志, 2016, 19(3): 381-384.

Wang Yi,Yang Zhenhua. Role of miRNAs in HBV infection and hepatocarcinogenesis[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2016, 19(3): 381-384.

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