实用肝脏病杂志 ›› 2011, Vol. 14 ›› Issue (2): 112-113.doi: 10.3969/j.issn.1672-5069.2011.02.010

• 论著 • 上一篇    下一篇

71例慢性乙型肝炎患者肝活检病理学分析

李小玲,罗小克,李照昕,王晓红,丁明修,姜凌   

  1. 125000辽宁省葫芦岛市 解放军第313医院医务处(李小玲);感染病科(罗小克,李照昕,王晓红);病理科(丁明修);超声科(姜凌)
  • 收稿日期:2010-12-06 修回日期:2016-04-15 出版日期:2011-04-10 发布日期:2016-04-15
  • 作者简介:李小玲 女,35岁,大学本科,主治医师。主要从事传染性疾病的诊断与治疗学研究及医疗管理工作。E-mail:lxl-yy@sohu.com

Analysis of pathological diagnosis of percutaneous liver biopsy in 71 patients with chronic hepatitis B

LI Xiaoling,LUO Xiaoke,LI Zhaoxin,et al.   

  1. Department of Infectious Disease,313rd Hospital of PLA,Huludao 125000,Liaoning Province,China
  • Received:2010-12-06 Revised:2016-04-15 Online:2011-04-10 Published:2016-04-15

摘要: 目的 探讨肝穿刺活检对慢性乙型肝炎诊断的临床意义。方法 对71例慢性乙型肝炎患者行经皮肝穿刺活体组织检查,分析临床诊断与病理学诊断的准确性。结果 在71例慢性乙型肝炎患者中,病理学诊断为G1为9.9%,G2和G3为59%,而G4为31%,诊断纤维化分期S1~S4分别为29%、25%、13%和32%,而临床诊断的灵敏度、阳性似然比、阳性预测值、Youden指数均偏低。结论 临床诊断慢性乙型肝炎病情程度的分度还不够准确,肝穿刺活检对诊断、治疗和预后判断等仍有着极其重要的意义。

关键词: 慢性乙型肝炎, 肝活检, 病理学

Abstract: Objective To explore the clinical significance of liver biopsy in patients with chronic hepatitis B. Methods The percutaneous liver biopsies were operated in 71 patients with CHB and the clinical diagnosis were assessed based on the pathological diagnosis. Results In the 71 patients with CHB,G1 to G4 were pathologically found in 9.9%,35%,24% and 31%,and S1 to S4 were 29%,25%,13% and 32%,respectively,while the sensitivity,specificity and accuracy of clinical diagnosis were relatively lower. Conclusion The percutaneous liver biopsy is vital to the diagnosis,treatment and prognosis of patients with chronic hepatitis B.

Key words: Hepatitis B, Liver biopsy, Pathological diagnosis