肝脏局灶性结节性增生磁共振表现特征分析*

doi:10.3969/j.issn.1672-5069.2026.03.034

实用肝脏病杂志 ›› 2026, Vol. 29 ›› Issue (3): 454-457.doi: 10.3969/j.issn.1672-5069.2026.03.034

• 肝脏局灶性结节性增生 • 上一篇下一篇

肝脏局灶性结节性增生磁共振表现特征分析^*

刘静芳, 胡孝娟, 杨卫健

222000 江苏省连云港市第二人民医院医学影像科(刘静芳,胡孝娟);南京中医药大学附属泰州医院医学影像科(杨卫健)

收稿日期:2024-11-01 出版日期:2026-05-10 发布日期:2026-05-18
通讯作者: 胡孝娟,E-mail:huxj_2008@163.com
作者简介:刘静芳,女,39岁,大学本科,主治医师。E-mail:liujf_2009@163.com
基金资助:
^*江苏省科技厅科研项目(编号:BE2022420)

MR imaging feature of focal nodular hyperplasia of liver: Analysis of 35 cases

Liu Jingfang, Hu Xiaojuan, Yang Weijian

Department of Radiology, Second People's Hospital, Lianyungang 222000, Jiangsu Province, China

Received:2024-11-01 Online:2026-05-10 Published:2026-05-18

摘要/Abstract

摘要： 目的总结分析一组肝脏局灶性结节性增生(FNH)病灶磁共振成像(MRI)表现特征。方法 2021年1月～2024年6月我院诊治的35例FNH患者,所有患者均于术前接受MRI平扫、增强扫描和DWI检查,行肝叶病灶切除术,术后组织病理学检查诊断。结果 35例肝脏FNH患者共检出63个结节病灶,呈分叶状或类圆形,以单发结节和肝右叶多见;病灶长径为0.5～14.3 cm,平均为(4.1±0.9)cm,其中结节病灶长径≤3.0 cm有41个,＞3.0 cm有22个;MRI序列信号表现为T₁WI呈等或稍低信号,T₂WI和DWI呈稍高信号,弥散无明显受限;多期动态增强扫描显示为“快进慢出”强化方式;＞3.0 cm病灶脂肪变性、局部坏死、假包膜、无中央瘢痕、动脉期强化不明显和肝胆期呈低信号占比分别为77.3%、68.2%、86.4%、63.6%、73.7%和63.6%,均显著高于≤3.0 cm病灶(分别为31.7%、24.4%、38.1%、29.3%、46.3%和26.9%,P＜0.05)。结论肝脏FNH病灶有特征性MRI表现,可作为临床鉴别诊断的重要依据。

关键词: 肝脏局灶性结节性增生, 磁共振表现, 特征, 诊断

Abstract: Objective The aim of this study was to summarize magnetic resonance imaging feature of focal nodular hyperplasia (FNH) of liver. Methods 35 patients with FNH were encountered in in our hospital from January 2021 to June 2024, and all underwent MR scan and hepatectomy for removal of the tumors. Diagnosis was confirmed by surgical tissue examination pathologically. Results Of the 35 patients with FNH, 63 nodules were found by MRI, present as lobulated or quasi-circular, main solitary, located in right lobe, with diameters of 0.5-14.3 cm (mean 4.1±0.9)cm, and lesions were ≤3.0 cm in 41 and ＞3.0 cm in 22; MRI sequence showed equal or slightly low signals on T₁WI, while slightly high signals on T₂WI and DWI, without diffusion limitation; multi-phase dynamic enhancement scan showed a fast-in and slow-out enhancement mode; proportions of steatosis, local necrosis, pseudocapsule, no central scar, no obvious enhancement at arterial phase and low signals at hepatobiliary phase in nodules with diameter >3.0 cm were 77.3%,68.2%, 86.4%, 63.6%, 73.7% and 63.6%, all significantly higher than 31.7%, 24.4%, 38.1%, 29.3%, 46.3% and 26.9% (P＜0.05) in those with diameter ≤3.0 cm. Conclusion MRI feature of FNH of liver is typical and some special, which might help clinicians differentiate it from malignant tumors.

Key words: Focal nodular hyperplasia of liver, Magnetic resonance imaging, Feature, Diagnosis

刘静芳, 胡孝娟, 杨卫健. 肝脏局灶性结节性增生磁共振表现特征分析^*[J]. 实用肝脏病杂志, 2026, 29(3): 454-457.

Liu Jingfang, Hu Xiaojuan, Yang Weijian. MR imaging feature of focal nodular hyperplasia of liver: Analysis of 35 cases[J]. Journal of Practical Hepatology, 2026, 29(3): 454-457.

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肝脏局灶性结节性增生磁共振表现特征分析^*

MR imaging feature of focal nodular hyperplasia of liver: Analysis of 35 cases

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