多层螺旋CT测定全肝体积/脾脏体积比对诊断肝硬化的价值研究

doi:10.3969/j.issn.1672-5069.2020.06.020

摘要/Abstract

摘要： 目的研究多层螺旋CT测定全肝体积与脾脏体积之比(TLV/SV)对肝硬化的诊断价值。方法 2016年10月～2019年10月我院收治的肝硬化患者138例和同期良性肝病或体检者130例,均行多层螺旋CT动态增强检查,应用Add/Remove Structure软件测量全肝体积(TLV)、右半肝体积(RV)、左内叶体积(LMV)、左外叶体积(LLV)、尾状叶体积(CV)、脾脏体积(SV)及TLV/RV、TLV/LMV、TLV/LLV、TLV/CV和TLV/SV比值。结果肝硬化组TLV、RV和LMV分别为(1078.2±315.7)cm³、(543.8±186.5)cm³和(163.6±73.7)cm³,显著低于对照组【分别为(1470.4±199.7)cm³、(933.3±174.1)cm³和(216.2±40.1)cm³,P＜0.05】,肝硬化组LLV和SV分别为(327.8±121.9)cm³和(863.4±396.8)cm³,显著高于对照组【分别为(275.9±65.7)cm³和(256.3±81.7)cm³,P＜0.05】;肝硬化组TLV/RV比值为2.0±0.9,显著高于对照组【(1.6±0.7),P＜0.05】,而TLV/LLV、TLV/CV和TLV/SV比值分别为(3.3±1.5)、(25.3±12.4)和(1.3±0.6),显著低于对照组【分别为(5.3±2.5、(32.8±16.1)和(5.7±2.4),P＜0.05】,两组CV和TLV/LMV比值比较差异无统计学意义(P＞0.05)。结论采用多层螺旋CT测定TLV/SV比值等参数在肝硬化诊断方面具有重要的临床价值。

关键词: 肝硬化, 多层螺旋CT, 全肝体积, 脾脏体积, 诊断

Abstract: Objective The aim of this study was to investigate the value of total liver volume (TLV)/spleen volume (SV) ratio by multislice CT calculation in diagnosis ofpatients with liver cirrhosis (LC). Methods 138 cirrhotic patients and 130 patients with benign liver diseases or healthy persons were admitted to our hospital between October 2016 and October 2019, and all underwent dynamic contrast-enhanced multi-slice spiral CT scan. The TLV, right liver volume (RV), left inner lobe volume(LMV), left outer lobe volume (LLV), cauda lobe volume (CV), SV as well as TLV/RV ratio, TLV/LMV ratio, TLV/LLV ratio, TLV/CV ratio and TLV/SV ratio were calculated by software. Results The TLV, RV and LMV of liver in patients with LC were (1078.2±315.7) cm³, (543.8±186.5) cm³ and (163.6±73.7) cm³, significantly smaller than [(1470.4±199.7) cm³, (933.3±174.1) cm³ and (216.2±40.1) cm³, respectively, P<0.05], while the LLV and SV were (327.8±121.9) cm³ and (863.4±396.8) cm³, both significantly larger than [(275.9±65.7) cm³ and (256.3±81.7) cm³, respectively,P<0.05] in the control; the TLV / RV ratio in patients with LC was 2.0±0.9, significantly higher than [1.6±0.7, P<0.05], while the TLV / LLV ratio, TLV / CV ratio and TLV / SV ratio were (3.3±1.5), (25.3±12.4) and (1.3±0.6), all significantly lower than [(5.3±2.5),( 32.8±16.1) and (5.7±2.4), respectively, P<0.05] in the control; there were no significant differences in CV and TLV/LMV ratio between the two groups (P>0.05). Conclusion The calculation of TLV/SV by multislice spiral CT scan might help diagnose LC in clinical practice.

Key words: Liver cirrhosis, Multi slice spiral CT scan, Total liver volume, Spleen volume, Diagnosis

孙浩, 朱桂娟, 陈小宇. 多层螺旋CT测定全肝体积/脾脏体积比对诊断肝硬化的价值研究[J]. 实用肝脏病杂志, 2020, 23(6): 837-840.

Sun Hao, Zhu Guijuan, Chen Xiaoyu. Total liver volume/spleen volume ratio by multislice CT calculation in diagnosis of patients with liver cirrhosis[J]. Journal of Practical Hepatology, 2020, 23(6): 837-840.

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