[1] Yokoyama A,Muramatsu T,Ohmori T,et al. Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis,1998,19:1383-1387. [2] Yokoyama A,Yokoyama T,Omori T,et al. Helicobacter pylori,chronic atrophic gastritis,inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive cancers and the risk for gastric cancer in alcoholic Japanese men. J Gastroenterol Hepatol,2007,22:210-217. [3] Salo JA. Ethanol-induced mucosal injury in rabbit oesophagus. Scand J Gastroenterol,1983,18:713-721. [4] Cohen SM,Ellwein LB. Cell proliferation in carcinogenesis. Science,1990,249:1007-1011. [5] Maier H,Born IA,Veith S,et al.The effect of chronic ethanol consumption on salivary gland morphology and function in the rat. Alcohol Clin Exp Res,1986,10:425-427. [6] Pschl G,Seitz HK. Alcohol and cancer. Alcohol,2004,39:1-11. [7] Alcohol drinking. IARC Working Group,Lyon,13-20 October 1987. IARC Monogr Eval Carcinog Risks Hum,1988,44:35-45. [8] Obe G,Anderson D. International commission for protection against environmental mutagens and carcinogens. ICPEMC Working Paper No. 15/1.Genetic effects of ethanol. Mutat Res,1987,186:177-200. [9] Kahraman A,Erkasap N,Ken T,et al. The antioxidative and antihistaminic properties of quercetin in ethanol induced gastric lesions. Toxi cology,2003,183(13):133-142. [10] Smith GS,Mercer DW,Cross JM,et al. Gastric injury induced by ethanol and ischemia reperfusion in the rat. Differing riles for lipid peroxidation and oxygen radicals. Dig Dis Sci,1996, 41(6):1157-1164. [11] Frank A,Seitz HK,Bartsch H,et al.Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver by diseases predisposing to hepatocarcinogenesis. Carcinogenesis,2004,25:1027-1031. [12] Fang JL,Vaca CE. Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers. Carcinogenesis 1997,18:627-632. [13] Secretan B,Straif K,Baan R,et al. A review of human carcinogens-part E:tobacco,areca nut,alcohol,coal smoke,and salted fish. Lancet Oncol,2009,l10:1033-1034. [14] Harty LC,Caporaso NE,Hayes RB,et al. Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers. J Natl Cancer Inst,1997,89:1698-1705. [15] Coutelle C,Fleury B,Quattrocchi P,et al. Laryngeal and oropharyngeal cancer,and alcohol dehydrogenase 3 and glutathione S-transferase M1 polymorphism. Hum Genet,1997,99:319-325. [16] Visap JP,Gtte K,Benesova M,et al. Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 3*1-allele possibly due to salivary acetaldehyde.Gut,2004,53:871-876. [17] Vkevinen S,Tillonen J,Agarwal D,et al.High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects:strong evidence for the local carcinogenic action of acetaldehyde. Alcohol Clin Exp Res,2000,24:873-877. [18] Homann N,Krkkinen P,Koivisto T,et al. Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa. J Natl Cancer Inst,1997,89:1692-1697. [19] Simanowski UA,Suter PM,Stickel F,et al. Oesophageal epithelial hyperregeneration following chronic ethanol ingestion: effect of age and salivary gland function. J Natl Cancer Inst,1993,85:2030-2033. [20] Luo HR,Wu GS,Pakstis AJ,et al. Origin and dispersal of atypical aldehyde dehydrogenase ALDH2487Lys. Gene,2009,435:96-103 [21] Cui RI,Kamatani Y,Takahashi A,et al. Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology,2009,137:1768-1775. [22] Yang SJ,Yokoyama A,Yokoyama T,et al. Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk:a meta-analysis. World J Gastroenterol,2010,16:4210-4220. [23] Zhang FF,Hou L,Terry MB,et al. Genetic polymorphisms in alcohol metabolism,alcohol intake and the risk of stomach cancer in Warsaw,Poland. Int J Cancer,2007,121:2060-2064. [24] Vkevinen S,Mentula S,Nuutinen H,et al. Ethanol-derived microbial production of carcinogenic acetaldehyde in achlorhydric atrophic gastritis. Scand J Gastroenterol,2002,37:648-655. (校对:陈从新) |