Abstract: Objective To observe the effects of goat milk powder diet on nutrition condition and synthetic function of liver in patients with hepatitis B-induced liver cirrhosis. Methods Eighty patients with hepatitis B-related liver cirrhosis were enrolled in this study,and 40 cases were treated with goat milk powder in treatment group and 40 cases were treated with regular dieteric were treatment in control group. Evaluation of nutrition condition and liver function tests were conducted for 12 weeks in both groups. Analyses were carried out by using t test. Results At 4 week and 8 week observation,there was no significant difference of nutrition indicators and liver synthetic funtion,including body mass index,arm muscle circumference,serum albumin,pre-albumim,transferrin and cholinesterase levels between the two groups;the body mass index [（23.36±1.26） kg/m² vs. （22.30±1.80） kg/m², t=3.021,P<0.05],arm muscle circumstance[（27.89±2.85） cm vs.（26.16±3.04） cm,t=2.766,P<0.05],albulmin [（34.93±1.63） g/L vs.（32.04±1.80） g/L,t=7.597,P<0.05],pre-albulmin [（91.97±21.14） mg/L vs. （76.92±15.94）mg/L,t=3.415,P<0.05],transferrin [（1.69±0.35） mg/L vs.（1.50±0.34） mg/L,t=2.315,P<0.05] and cholinesterase[（2785±516）U/L vs.（2546±487） U/L,t=2.105,P<0.05] in the treatment group at week 12 were significantly increased as compared to those in the control group,while the serum levels of total bilirubin,blood ammonia, plasma triglyceride and blood sugar showed no significant differences between the two groups. Conclusions Dietary intervention with goat milk powder can improve nutrition condition and liver synthetic function in patients with hepatitis B-induced liver cirrhosis.

Key words: Liver cirrhosis, Hepatitis B, Goat milk powder, Nutrition