JOURNAL OF PRACTICAL HEPATOLOGY ›› 2014, Vol. 17 ›› Issue (1): 98-102.doi: 10.3969/j.issn.1672-5069.2014.01.032

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Serum HBsAg and HBeAg levels in the prediction of antiviral efficacy in patients with chronic hepatitis B

Lin Hu, Li Yuanyuan, Wang Fusheng   

  1. Center for Biological Therapy of Liver Disease,302nd Hospital,Beijing 100039,China
  • Received:2012-11-04 Online:2014-02-28 Published:2016-04-11

Abstract: Quantification of serum HBsAg and HBeAg in patients with CHB is useful in the prediction of response to antiviral treatment, and they can be used to guide the treatment strategy. Here we reviewed the changes in serum HBsAg and HBeAg levels in patients with CHB and their relations to HBV replication, which include serum HBV DNA, and intrahepatic HBV cccDNA. This review will help to understand the clinical value of serum HBsAg and HBeAg levels in the prediction of antiviral efficacy in patients with CHB.

Key words: Chronic hepatitis B, Hepatitis B virus, HBsAg, HBeAg, Antiviral treatment