Abstract: Objective The purpose of this study was to compare the efficacy of microwave ablation (MWA) and laparoscopic hepatectomy (LH) in the treatment of patients with hepatic hemangiomas (HH). Methods 94 patients with HH were admitted to our hospital between January 2018 and March 2022, and were divided into two groups, receiving MWA in 46 cases and LH in 48 cases. All patients were followed-up for 1 year after operation. Serum tumor necrosis factor -α (TNF-α) and interleukin-6 (IL-6) levels were determined by ELISA. Results The intraoperative blood loss, blood flow blocking time, operation time and hospital stay in MWA-treated patients were (17.2±3.5)mL, (22.8±4.4)min, (158.0±31.8)min and (6.3±1.9)d, all significantly less or shorter than [(208.4±39.7) mL, (26.3±5.1)min, (228.5±43.2)min and (8.1±2.4)d, respectively, P<0.05] in patients receiving LH treatment; there were no significant differences as respect to liver function tests between the two groups before and after operation (P>0.05); five days after operation, serum TNF-α and IL-6 levels in patients with MWA treatment were (51.3±7.5)pg/ml and (18.3±3.5)pg/ml, both significantly lower than [(65.9±10.4)pg/ml and (26.8±4.9)pg/ml, respectively, P<0.05] in LH-treated patients; the incidences of post-operational complications, such as infections and bile leakage, in MWA- and LH-treated patients were 4.4% and 8.3% (P>0.05); at the end of one-year follow-up, no intrahepatic tumors relapsed in LH-treated patients, and the tumors shrank to 25% in 43 cases (93.5%) in MWA-treated patients. Conclusion The patients with HH could be managed by both MWA or LH, but we recommend the former because of the less body inflammatory reactions and rapid recovery.

Key words: Hepatic hemangiomas, Microwave ablation, Laparoscopy hepatectomy, Treatment