Journal of Practical Hepatology ›› 2023, Vol. 26 ›› Issue (5): 765-768.doi: 10.3969/j.issn.1672-5069.2023.05.041

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Mechanism of Shuganning’s roles in promoting gallbladder motion, relieving jaundice, anti-inflammatory and protecting liver functions

Huang Long, Fan Yaxi, Duan Zhongping   

  1. Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Fourth Department of Liver Disease Center, You’an Hospital, Capital Medical University, Beijing 100069, China
  • Received:2022-05-05 Online:2023-09-10 Published:2023-09-13

Abstract: With the in-depth development of liver disease research with integrated traditional Chinese and Western medicine, new approaches and new medicines for liver disease treatment continue to emerge. The traditional Chinese medicine single-target superposition, multi-target synergistic effects and toxic dispersion effects provide more ideas for liver disease treatment and become a rich source of an important way to improve the treatment of liver disease. In this paper, we introduce the mechanism of Shuganning, a herbal medicine compound, in relieving bile and reducing jaundice from the perspectives as follows: liver transporters, metabolic enzymes and nuclear receptors, and its anti-inflammatory and hepatoprotective mechanism.

Key words: Viral hepatitis, Nonalcoholic fatty liver disease, Shuganning injection, mechanism, Treatment