Journal of Practical Hepatology ›› 2020, Vol. 23 ›› Issue (3): 401-404.doi: 10.3969/j.issn.1672-5069.2020.03.025

• Liver cirrhosis • Previous Articles    

Clinical characteristics and risk factors of portal vein thrombosisin patients with liver cirrhosis

Rinat·Kirim, Turganaili·Aj, Shao Yinmei.   

  1. Department of Hepatobiliary Surgery, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054
  • Published:2020-05-27

Abstract: Objective The aim of this study was to analyze the clinical characteristics and risk factors of portal vein thrombosis (PVT) in patients with liver cirrhosis (LC). Methods A retrospective analysis was made on 160 patients with LC admitted to our Department in our hospital from February 2015 through February 2019. The clinical symptoms, laboratory indexes and general data of patients were collected. The multivariate Logistic analysis was applied to evaluate the risk factors of PVT. Results The incidence of abdominal pain, ascites and gastrointestinal hemorrhage, and the platelet (PLT) counts and white blood cell (WBC) counts in 80 patients with PVT were significantly higher than those in 80 patients without PVT; the multivariate Logistic analysis showed that the PLT counts, diabetes and splenectomy were the independent risk factors for PVT in patients with LC (P<0.05). Conclusion The ascites, gastrointestinal hemorrhage and liver dysfunction are the main clinical manifestation in patients with LC and PVT, and the PLT counts, diabetes and splenectomy are the main independent risk factors for portal vein thrombosis.

Key words: Liver cirrhosis, Portal vein thrombosis, Platelets, Diabetes mellitus, Splenectomy, Risk factors