JOURNAL OF PRACTICAL HEPATOLOGY ›› 2019, Vol. 22 ›› Issue (3): 417-420.doi: 10.3969/j.issn.1672-5069.2019.03.027

• Liver cirrhosis • Previous Articles     Next Articles

Predictive value of preoperative CT/MRI indicators for portal vein thrombosis in patients with liver cirrhosis after splenectomy

Xiao Ke, Pan Zhihua, Tu Bo   

  1. Department of Radiology,Second Affiliated Hospital,Chengdu Medical College,Chengdu 610051,Sichuan Province,China
  • Received:2018-12-12 Online:2019-05-10 Published:2019-05-15

Abstract: Objectiv The aim of this study was to investigate the predictive value of preoperative CT/MRI indicators for portal vein thrombosis(PVT) in patients with liver cirrhosis after splenectomy. Methods 87 patients with hepatitis B liver cirrhosis after splenectomy were retrospectively analyzed in our hospital between July 2016 and July 2018,and all patients were followed-up and underwent CT and MRI check-up. Multivariate logistic regression analysis was applied to predict the independent influencing factors of PVT formation after splenectomy. Results At the end of three-month follow-up,46 patients (52.9%) had PVT out of the 87 patients with cirrhosis,belonging to typeⅠPVT,and mural thrombus was found in 45 patients(51.7%),out of which,14(16.1%) as mural thrombus in superior mesenteric vein;the diameter of portal vain in 46 patients with PVT was(16.7±2.2)mm,significantly wider than 【(14.8±1.5) mm,P<0.05】 in 41 patients without PVT,the difference of portal vein velocity was (8.4±5.5) cm/s, significantly rapider than [(6.1±3.6) cm/s,P<0.05] in non-PVT group and the spleen volume was (1370.8±370.1) cm3,significantly larger than [(1205.2±357.3) cm3,P<0.05] in non-PVT group;multivariate logistic regression analysis showed that the diameter of portal vein(OR=0.869,95%CI=0.608-1.246),the velocity difference of portal vein(OR=1.185,95%CI=1.079-1.317),and the spleen volume(OR=3.427,95%CI=2.215-5.302) were the independent influencing factors of PVT formation after splenectomy in patients with cirrhosis (P<0.05). Conclusion Preoperative CT/MRI diagnostic indexes such as portal vein diameter,portal vein velocity difference and spleen volume are independent influencing factors of PVT formation after splenectomy for liver cirrhosis.

Key words: Liver cirrhosis, Splenectomy, Portal vein thrombosis, CT, MRI