Journal of Practical Hepatology ›› 2023, Vol. 26 ›› Issue (6): 930-933.doi: 10.3969/j.issn.1672-5069.2023.06.041

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Perspective of betatrophin in the development of nonalcoholic fatty liver diseases

Han Shishan, Zhao Caiyan   

  1. Department of Infectious Diseases, Third Hospital,Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
  • Received:2023-02-02 Online:2023-11-10 Published:2023-11-20

Abstract: Objective Nonalcoholic fatty liver diseases (NAFLD) is a kind of liver injury caused by metabolic stress. With the prevalence of obesity and metabolic syndrome (MetS), the NAFLD has become the most popular chronic liver disease in China. Betatrophin is a newly discovered glycoprotein closely related to glucose and lipid metabolism and insulin resistance (IR), which may be closely related to the onset and progression of NAFLD. This article reviewed the role of betatrophin in the process and development of NAFLD.

Key words: Nonalcoholic fatty liver diseases, Betatrophin, Glucose and Lipid metabolism, Insulin resistance