Abstract: Objective The aim of this study was to summarize the clinical features, treatment and prognosis of patients with Fitz-Hugh-Curtis syndrome. Methods The clinical data of 7 patients with Fitz-Hugh-Curtis syndrome in our hospital between January 2016 and April 2021 were retrospectively summarized, including general feature, symptoms and signs, laboratory test results, initial diagnosis, imaging manifestation, gynecological examination, treatment and outcomes. Results All the 7 patients were young women, with the onset of acute abdominal pain; the hepatic capsule enhancement in arterial phase, the uniform enhancement or weakening of liver capsule and liver parenchyma in portal phase and delayed phase were observed in all the 7 cases by abdominal contrast-enhanced CT scan; the acute cholecystitis in 2 cases, acute pancreatitis in 2 cases, and peptic ulcer in 1 case were initially diagnosed before abdominal CT scan; the vaginal secretion examination showed the chlamydia trachomatis in 4 cases; all the 7 patients were treated with ceftriaxone, doxycycline and/or metronidazole combination for two weeks, and all of them recovered. Conclusion In young women at reproductive age with sexual life, the acute onset of persistent epigastric pain or right epigastric pain might hints the Fitz-Hugh-Curtis syndrome, and the diagnosis could be made by gynecological and imaging examination.

Key words: Fitz-Hugh-Curtis syndrome, Abdominal pain, Abdominal enhanced CT scan, Feature