JOURNAL OF PRACTICAL HEPATOLOGY ›› 2015, Vol. 18 ›› Issue (1): 105-108.doi: 10.3969/j.issn.1672-5069.2015.01.030

• Orignal Article • Previous Articles     Next Articles

What's new The definition,diagnosis and management of HBV-related pre- acute-on-chronic liver failure

Li Chen, You Shaoli, Xin Shaojie   

  1. Medical School of Chinese PLA,302nd Hospital,Beijing 100853
  • Received:2014-05-28 Online:2015-12-17 Published:2015-12-17

Abstract: Hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF),characterized by rapid disease progression and high mortality,is a serious health problem in China. The outcomes will differ if the clinicians can diagnose the patients with ACLF in time and give them instant intervention. So some scholars in the world began to study the patients in so-called pre-liver failure stage. The scholars in the west,Hong Kong and Taiwan defined it as severe acute exacerbation of chronic hepatitis B,while the scholars in the mainland tried to set up three different diagnostic criteria for pre-ACLF. This review mainly focuses on recent advances in the definition, diagnosis and treatment of patients with HBV-related pre-ACLF.

Key words: Hepatitis B, Liver failure, Pre-stage, Diagnosis, Treatment