JOURNAL OF PRACTICAL HEPATOLOGY ›› 2014, Vol. 17 ›› Issue (5): 484-489.doi: 10.3969/j.issn.1672-5069.2014.05.010

• Orignal Article • Previous Articles     Next Articles

A correlation of liver stiffness to controlled attenuation parameter in healthy individuals

Lu Jiafa, Liu Wenbin, Pan Qin   

  1. Department of Gastroenterology,Xinhua Hospital,Shanghai JiaoTong University School of Medicine,Shanghai 200092,China
  • Received:2014-04-26 Online:2014-10-31 Published:2016-04-11

Abstract: Objective To explore the correlation between liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in the general population. Methods A correlation of LSM to CAP was conducted in a total of 207 participants who were successfully examined by FibroScan in a general health examination,and the data including gender,age,body mass index(BMI) and waist height radio (WHtR) were recorded. Results The LSM and CAP in overweight and obese participants (BMI≥24 kg/m2) were higher than those in lean participants (BMI<24 kg/m2) [(4.60±1.15)kPa vs. (4.25±1.23)kPa,P<0.001 and (245.24±55.37) dB/m vs.(215.82±55.47) dB/m,P<0.001];participants with WHtR≥0.50 had higher LSM and CAP as compared to those with WHtR<0.50 [(4.52±1.22) kPa vs.(4.19±1.15) kPa,P<0.05 and(247.04±57.78) dB/m vs.(204.65±52.25) dB/m,P<0.05];male participants had higher LSM and CAP than in female [(4.53±1.23)kPa vs.(4.11±1.08) kPa,P<0.05 and (4.11±1.08) dB/m vs.(220.08±57.88) dB/m,P<0.05]; the CAP was higher in participants older than 50 years as compared to participants under 50 years[(246.56±59.06)dB/m vs.(222.88±56.60) dB/m,P<0.01],while the LSM in the two groups showed no difference(P>0.05);The LSM was significantly correlated with CAP in this cohort(r=0.26,P=0.0002);Further analysis demonstrated that CAP was correlated with LSM in male,older than or equal to 50 years,