关键词: 慢性乙型肝炎, 肝脂肪变, 危险因素, 代谢综合征, 男性

Abstract: Objective To analyze the difference in clinical features between male chronic hepatitis B（CHB） patients with or without hepatic steatosis and to search for the risk factors for hepatic steatosis. Methods Two hundred and nine male patients with CHB who were hospitalized for the first time and underwent liver biopsy from March 2010 to March 2013 were included in this study，and the patients were divided into two groups according to the presence or absence of hepatic steatosis；Serum lipids，uric acid，glucose，alcohol consumption， obesity，overweight and hepatitis B virus DNA load between the two groups were compared，and risk factors for hepatic steatosis were analyzed using binary logistic regression. Results Among the 209 patients，there were 121 cases（57.9%） with and 88（42.1%） without hepatic steatosis；Uric acid，low density lipoprotein and triglyceride were （352.5±87.1） mmol/L，（2.8±0.8） mmol/L and （1.8±0.1） μmol/L，respectively，in CHB patients with hepatic steatosis， all of which were remarkably higher than those in CHB patients without steatosis [（310.3±69.1）mmol/L，（2.2±0.6） mmol/L and（1.2±0.7）μmol/L， respectively，P<0.01）]；Obesity，overweight and low density lipoprotein were the risk factors for hepatic steatosis（P<0.01）. Conclusions Obesity and hyperlipidemia， but not viral load and alcohol consumption，are the risk factors for hepatic steatosis in male patients with CHB.

Key words: Chronic hepatitis B, Hepatic steatosis, Risk factors, Metabolic syndrome, Male