关键词: 肝门部胆管癌, 肝动脉切除重建, 门静脉切除重建, 常规根治术

Abstract: Objective The aim of this study was to investigate prognosis of patients with hilar cholangiocarcinoma (HC) after reconstruction of hepatic artery or of portal vein and conventional radical hepatectomy. Methods 70 patients with HC admitted to our hospital between March 2014 and January 2017 were divided randomly into group A (n=24), receiving radical hepatectomy and hepatic artery resection and reconstruction, group B (n=23), receiving radical hepatectomy and portal vein resection and reconstruction, and group C (n=23), receiving conventional radical hepatectomy. All patients were followed-up for 32 to 46 months, with a median of 36 months. Results In group A, the operation time was (11.4±2.6) h, significantly longer than in group B and in group C , the intraoperative blood loss was (914.5±175.0) ml, significantly higher than in group B and in group C , the exhaust time was (23.2±11.8) h, significantly longer than in group B and in group C , the hospitalization stay was (21.6±7.2) d, significantly longer than in group B and in group C ; the 1-year,2-year and 3-year survival rates in group A were 66.7%,41.7% and 33.3%, respectively, which were significantly lower than 91.3%,73.9% and 52.2% in group B (P<0.05) or 87.0%, 69.6% and 47.8% in group C (P<0.05).Conclusion The combination of hepatectomy and reconstruction of radical hepatectomy is not superior to conventional radical surgery in the treatment of patients with HC, so we don’t recommend this procedure in clinical practice.

Key words: Hilar cholangiocarcinoma, Hepatic artery resection and reconstruction, Portal vein resection and reconstruction, Radical hepatectomy