非酒精性脂肪性肝病与高尿酸血症

doi:10.3969/j.issn.1672-5069.2017.03.002

实用肝脏病杂志 ›› 2017, Vol. 20 ›› Issue (3): 260-262.doi: 10.3969/j.issn.1672-5069.2017.03.002

非酒精性脂肪性肝病与高尿酸血症

徐承富, 厉有名

310003 杭州市浙江大学医学院附属第一医院消化科

收稿日期:2017-03-03 出版日期:2017-06-10 发布日期:2018-03-10
通讯作者: 厉有名,E-mail: zlym@zju.edu.cn
作者简介:徐承富,男,34岁,医学博士,副研究员,副主任医师,博士生导师

Hyperuricemia in patients with nonalcoholic fatty liver disease

Xu Chengfu, Li Youming

Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China

Received:2017-03-03 Online:2017-06-10 Published:2018-03-10
Contact: Corresponding author: Li Youming, E-mail:zlym@zju.edu.cn

摘要/Abstract

关键词: 非酒精性脂肪性肝病, 高尿酸血症, 患病率, 发病率

Key words: Nonalcoholic fatty liver disease, Hyperuricemia, Prevalence, Incidence

徐承富, 厉有名. 非酒精性脂肪性肝病与高尿酸血症[J]. 实用肝脏病杂志, 2017, 20(3): 260-262.

Xu Chengfu, Li Youming. Hyperuricemia in patients with nonalcoholic fatty liver disease[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2017, 20(3): 260-262.

[1] Fan JG.Epidemiology of alcoholic and nonalcoholic fatty liver disease in China. J Gastroenterol Hepatol,2013,28(Suppl 1):11-17.
[2] Lonardo A,Loria P,Leonardi F,et al.Fasting insulin and uric acid levels but not indices of iron metabolism are independent predictors of non-alcoholic fatty liver disease. A case-control study. Dig Liver Dis,2002,34(3):204-211.
[3] Lee S,Jin Kim Y,Yong Jeon T,et al.Obesity is the only independent factor associated with ultrasound-diagnosed non-alcoholic fatty liver disease:a cross-sectional case-control study. Scand J Gastroenterol,2006,41(5):566-572.
[4] Baba T,Amasaki Y,Soda M,et al.Fatty liver and uric acid levels predict incident coronary heart disease but not stroke among atomic bomb survivors in Nagasaki. Hypertens Res,2007,30(9):823-829.
[5] Li Y,Xu C,Yu C,et al.Association of serum uric acid level with non-alcoholic fatty liver disease: a cross-sectional study. J Hepatol,2009,50(5):1029-1034.
[6] Cai W,Wu X,Zhang B,et al.Serum uric acid levels and non-alcoholic fatty liver disease in Uyghur and Han ethnic groups in northwestern China. Arq Bras Endocrinol Metabol,2013,57(8):617-622.
[7] Moon SS.Relationship between serum uric acid level and nonalcoholic fatty liver disease in pre- and postmenopausal women. Ann Nutr Metab,2013,62(2):158-163.
[8] Liu PJ,Ma F,Lou HP,et al.Relationship between serum uric acid levels and hepatic steatosis in non-obese postmenopausal women. Climacteric,2014,17(6):692-699.
[9] Xia MF,Lin HD,Li XM,et al.Renal function-dependent association of serum uric acid with metabolic syndrome and hepatic fat content in a middle-aged and elderly Chinese population. Clin Exp Pharmacol Physiol,2012,39(11):930-937.
[10] Liu CQ,He CM,Chen N,et al. Serum uric acid is independently and linearly associated with risk of nonalcoholic fatty liver disease in obese Chinese adults. Sci Rep,2016,[ahead of print].
[11] Cardoso AS,Gonzaga NC,Medeiros CC,et al.Association of uric acid levels with components of metabolic syndrome and non-alcoholic fatty liver disease in overweight or obese children and adolescents. J Pediatr (Rio J),2013,89(4):412-418.
[12] Petta S,Camma C,Cabibi D,et al.Hyperuricemia is associated with histological liver damage in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther,2011,34(7):757-766.
[13] Sertoglu E,Ercin CN,Celebi G,et al.The relationship of serum uric acid with non-alcoholic fatty liver disease. Clin Biochem,2014,47(6):383-388.
[14] Liu J,Xu C,Ying L,et al. Relationship of serum uric acid level with non-alcoholic fatty liver disease and its inflammation progression in non-obese adults. Hepatol Res,2016,[ahead of print].
[15] Yoneda M,Thomas E,Sumida Y,et al.Uric acid levels decrease with fibrosis progression in patients with nonalcoholic fatty liver disease. Clin Biochem,2014,47(12):1138-1139.
[16] Huang JF,Yeh ML,Yu ML,et al.Hyperuricemia inversely correlates with disease severity in Taiwanese nonalcoholic steatohepatitis patients. PLoS One,2015,10(10):e0139796.

非酒精性脂肪性肝病与高尿酸血症

Hyperuricemia in patients with nonalcoholic fatty liver disease

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