体检人群非酒精性脂肪性肝病检出率及其相关因素分析*

doi:10.3969/j.issn.1672-5069.2012.04.007

实用肝脏病杂志 ›› 2012, Vol. 15 ›› Issue (4): 289-290.doi: 10.3969/j.issn.1672-5069.2012.04.007

体检人群非酒精性脂肪性肝病检出率及其相关因素分析^*

王春霞, 麦韵屏, 沙卫红, 王启仪

510080 广州市广东省人民医院/广东省医学科学院消化内科

收稿日期:2012-03-06 出版日期:2012-08-10 发布日期:2017-03-15
通讯作者: 王启仪,E-mail：qiyiw@163.com
作者简介:第一作者：王春霞,汕头大学医学院消化内科专业硕士研究生
基金资助:
本研究受广东省科技计划项目资助（00080711120302025）

Prevalence and risk factors of non-alcoholic fatty liver disease in checked-up individuals

Wang Chunxia, Mai Yunping, Sha Weihong, et al.

Department of Gastroenterology and Hepatology,General Hospital,Guangdong Academic of Medical Science,Guangzhou 510080

Received:2012-03-06 Online:2012-08-10 Published:2017-03-15
Contact: Corresponding author:Wang Qiyi,E-mail：qiyiw@163.com

摘要/Abstract

摘要： 目的探讨广东地区不同年龄段体检人群非酒精性脂肪性肝病（NAFLD）患病率及相关因素。方法对20047例体检人群进行B超和血生化学检查。结果本组体检人群NAFLD检出率为13.2%,其中单纯性非酒精性脂肪肝检出率为8.7%（1731/20047）,非酒精性脂肪性肝炎为4.5%（910/20047）,未检出肝硬化和肝癌;随年龄增长,NAFLD检出率逐渐增高,其中60~70岁年龄组人群检出率为25.6%,50~60岁年龄组为23.8%,与小于30岁组、30-岁组、40-岁组和70-岁组比,差异有统计学意义（分别为4.7%、10.8%、17.6%和18.7%,P<0.01）;男性人群NAFLD检出率高于女性（18.8%对7.8%,P<0.01）,但在60岁以上人群,男性与女性NAFLD检出率无明显差别（22.1% 对22.4%,P=0.883）;NAFLD患者合并高血压、高血糖、高甘油三酯血症和高胆固醇血症的发生率均高于无NAFLD人群（35.2% 对 11.7%,14.4% 对2.6%,46.8% 对10.1%,31.8% 对2.5%,P<0.01）。结论NAFLD的发病与年龄、性别及高血压、高血糖、高甘油三酯血症和高胆固醇血症等因素相关。

关键词: 非酒精性脂肪性肝病, 高血压, 高血糖, 高血脂, 体检人群

Abstract: Objective The aims of this study was to investigate the prevalence and risk factors of non-alcoholic fatty liver disease（NAFLD）in checked-up subjects in Guangdong Province. Methods 20047 subjects were checked-up by ultrasound and blood parameters. Results The prevalence of NAFLD in this subjects was 13.2%,in which the prevalence of NAFLD in male subjects was significantly higher than that in the female subjects（18.8% vs 7.8%,P<0.01）;the peak prevalence（23.8% to 25.6%） occurred in persons of 50- to 69-year old age,which were obviously higher than those in the other groups（4.7% in younger than 30,10.8% in younger than 40,17.6% in younger than 50 and 18.7% in older than 79 years of age,P<0.01）;Individuals with hypertension,hyperlipidemia and hyperglycemia had higher prevalence of NAFLD than those without（31.3% vs. 10.0%,41.3% vs. 8.2%,and 27.9% vs. 10.6%,P<0.01）. Conclusions The prevalence of NAFLD is high in Guangdong Province and there is a closed correlation of NAFLD to hypertension,hyperlipidemia and hyperglycemia.

Key words: Non-alcoholic fatty liver disease, Prevalence, Hypertension, Hyperlipidemia, Individuals

王春霞, 麦韵屏, 沙卫红, 王启仪. 体检人群非酒精性脂肪性肝病检出率及其相关因素分析^*[J]. 实用肝脏病杂志, 2012, 15(4): 289-290.

Wang Chunxia, Mai Yunping, Sha Weihong, et al.. Prevalence and risk factors of non-alcoholic fatty liver disease in checked-up individuals[J]. JOURNAL OF PRACTICAL HEPATOLOGY, 2012, 15(4): 289-290.

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体检人群非酒精性脂肪性肝病检出率及其相关因素分析^*

Prevalence and risk factors of non-alcoholic fatty liver disease in checked-up individuals

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