实用肝脏病杂志 ›› 2018, Vol. 21 ›› Issue (6): 983-986.doi: 10.3969/j.issn.1672-5069.2018.06.040

• 综述 • 上一篇    下一篇

自身免疫性肝炎诱发因素研究进展

夏庚综述, 祁飞, 杨晋辉审校   

  1. 650500 昆明市 昆明医科大学第二附属医院消化内科二病区
  • 收稿日期:2017-08-20 出版日期:2018-11-10 发布日期:2018-12-25
  • 通讯作者: 杨晋辉,E-mail:yangjinhui110415@sina.com
  • 作者简介:夏庚,男,28岁,硕士研究生。主要从事自身免疫性肝病的诊疗研究

Predisposing factors to autoimmune hepatitis

Xia Geng, Qi Fei, Yang Jinhui.   

  1. Department of Gastroenterology,Second Affiliated Hospital,Kunming Medical University,Kunming 650500,Yunnan Province
  • Received:2017-08-20 Online:2018-11-10 Published:2018-12-25

摘要: 自身免疫性肝炎是一种由针对肝细胞的自身免疫反应所介导的肝脏实质性炎症。各种因素能诱导自身免疫性肝炎的发生发展,目前认识的主要诱导因素有药物、感染、环境、年龄、性别、遗传等,但诱导机制仍不十分清楚。了解诱导因素可对防治疾病有帮助。

关键词: 自身免疫性肝炎, 诱导因素, 发病机制

Abstract: Autoimmune hepatitis is a parenchymal inflammation of liver that is mediated by autoimmune response to hepatocytes. There are various factors which can induce autoimmune hepatitis such as drugs,infection,environment,age,gender and genetic factors. However,the mechanism of induction is still not yet very clear,and the illumination of these factors might help prevent and manage the disease. In this review,we will do a brief overview of each of the above mentioned induction factors.

Key words: Autoimmune hepatitis, Predisposing factors, Mechanism