JOURNAL OF PRACTICAL HEPATOLOGY ›› 2010, Vol. 13 ›› Issue (4): 263-264.doi: 10.3969/j.issn.1672-5069.2010.04.008

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T-lymphocyte subsets levels on the efficacy of adefovir in the treatment of patients with chronic hepatitis B

JIANG Yangkun,TU Yanyun,XU Jian,et al.   

  1. Ruikang Hospital,Affiliated to Guangxi TCM University,Nanning 530011,Guangxi,China
  • Received:2009-12-06 Online:2010-08-10 Published:2016-04-18

Abstract: Objective To observe the efficacy of adefovir on patient with CHB. Method 42 CHB patients were divided into two groups based on the ratio of CD4+/CD8+. Two groups received adefovir for 12 months. Results After 12 months treatment,the high level group got a better improvement in the liver function,HBV DNA loss and HbeAg negative rate. Conclusion Pre-treatment levels of T lymphocyte subgroup in CHB will influence the efficacy of adefovir dipivoxil treatment.

Key words: Chronic hepatitis B, T lymphocyte subset, Adefovir, Afficacy