Abstract: Objective This study was designed to compare fast track surgery with conventional perioperative management in primary hepatic cancer patients undergoing lobular resection. Methods 53 primary hepatic cancer patients undergoing lobular resection were recruited for this comparative study. 23 patients received perioperative fast track rehabilitation，and 30 received conventional perioperative care. Outcomes were assessed by postoperative hospital stay，liver function tests and medical costs. Results Fast track rehabilitation group was associated with a significantly shorter postoperative hospital stay，less medical costs，earlier first passage of flatus in the postoperative period compared with conventional care group. Conclusion Fast track rehabilitation is feasible and effective in primary liver cancer patients undergoing resection.

Key words: Primary hepatic cancer, Liver resection, Fast track surgery