[1] PAREKKADAN B，VAN POLL D，SUGANUMA K，et al. Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure[J]. PLoS ONE，2007，2（9）:e941.
[2] BANAS A，TERATANI T，YAMAMOTO Y，et al. Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure[J]. J Gastroenterol Hepatol，2009，24（1）:70-77.
[3] ALISON MR，ISLAM S，LIM S. Stem cells in liver regeneration，fibrosis and cancer:the good，the bad and the ugly[J]. J Pathol，2009，217（2）:282-298.
[4] YAGI H，PAREKKADAN B，SUGANUMA K，et al. Long term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure[J]. Tissue Eng Part A，2009，15（11）:3377-3388.
[5] KUO TK，HUNG SP，CHUANG CH，et a1. Stem cell therapy for liver disease:parameters governing the success of using bone marrow mesenchymal stem cells[J]. Gastroenterology，2008，134（7）:2111-2121.
[6] BANAS A，TERATANI T，YAMAMOTO Y，et al. IFATS collection: in vivo therapeutic potential of human adipose tissue mesenchymal stem cells after transplantation into mice with liver injury[J]. Stem Cells，2008，26（10）:2705-2712.
[7] MOHAMADNEJAD M，ALIMOGHADDAM K， MOHYEDDIN-BONAB M，et al. Phase I trial of autologous bone marrow mesenchymal stem cell transplantation in patients with decompensated cirrhosis[J]. Arch Iran Med，2007，10（4）:459-466.
[8] KHARAZIHA P，HELLSTR e M PM，NOORINAYER B， et al. Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection:a phase I-II clinical trial[J]. Eur J Gastroenterol Hepatol，2009，21（10）:1199-1205.
[9] MIRANDA PS，BOSMA PJ. Towards liver-directed gene therapy for Crigler-Najjar syndrome[J]. Curr Gene Ther， 2009，9（2）:72-82.
[10] KHAN AA，PARVEEN N，MAHABOOB VS，et al. Treatment of Crigler-Najjar syndrome type 1 by hepatic progenitor cell transplantation:a simple procedure for management of hyperbilirubinemia[J]. Transplant Proc，2008，40（4）:1148-1150.
[11] FROSSARD V，KETTERER N，ROSSELET A，et al. Early intensification and autologous stem cell transplantation in patients with systemic AL amyloidosis:a single-centre experience[J]. Ann Hematol，2009，88（7）:681-685.
[12] ZHOU P，HOHM S，OLUSANYA Y，et al. Human progenitor cells with high aldehyde dehydrogenase activity efficiently engraft into damaged liver in a novel model[J]. Hepatology，2009，49（6）:1992-2000.
[13] FERREIRA E，POTIER E，LOGEART-AVRAMOGLOU D，et al. Optimization of a gene electrotransfer method for mesenchymal stem cell transfection[J]. Gene Ther，2008，15（7）:537-544.
[14] ORTIZ LA，DUTREIL M，FATTMAN C，et al. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury[J]. Proc Natl Acad Sci USA，2007，104（26）:11002-11007.
[15] VAN POLL D，PAREKKADAN B，CHO CH，et al. Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo[J]. Hepatology，2008，47（5）:1634-1643.
[16] TSAI PC，FU TW，CHEN YM，et al. The therapeutic potential of human umbilical mesenchymal stem cells from Wharton’s jelly in the treatment of rat liver fibrosis[J]. Liver Transpl，2009，15（5）:484-495.
[17] PAREKKADAN B，VAN POLL D，MEGEED Z，et al. Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells[J]. Biochem. Biophys Res Commun，2007，363（2）:247-252.
[18] HIGASHIYAMA R，INAGAKI Y，HONG YY，et al. Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice[J]. Hepatology，2007，45（1）:213-222.
[19] CARVALHO AB，QUINTANILHA LF，DIAS JV，et al. Bone marrow multipotent mesenchymal stromal cells do not reduce fibrosis or improve function in a rat model of severe chronic liver injury[J]. Stem Cells，2008，26（5）:1307-1314.
[20] WANG Y，WEIL BR，HERRMANN JL，et al. MEK， p38 and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells[J]. Am J Physiol Cell Physiol，2009，297（5）:C1284-1293.
[21] WANG Y，WANG M，ABARBANELL AM，et al. MEK mediates the novel cross talk between TNFR2 and TGF-EGFR in enhancing vascular endothelial growth factor （VEGF）secretion from human mesenchymal stem cells[J]. Surgery，2009，146（2）:198-205.
[22] CRISOSTOMO PR，WANG Y，MARKEL TA，et al. Human mesenchymal stem cells stimulated by TNF-alpha， LPS，or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism[J]. Am J Physiol Cell Physiol，2008，294（3）:C675-682.
[23] AURICH H，SGODDA M，KALTWASSER P，et al. Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo[J]. Gut，2009，58（4）:570-581.
[24] BONORA-CENTELLES A，JOVER R，MIRABET V，et al. Sequential hepatogenic trans-differentiation of adipose tissue-derived stem cells:relevance of different extracellular signaling molecules，transcription factors involved and expression of new key marker genes[J]. Cell Transplant， 2009，18（12）:1319-1340.
[25] BANAS A，TERATANI T，YAMAMOTO Y，et al. Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure[J]. J Gastroenterol Hepatol，2009，24（1）:70-77.
[26] DENG X，CHEN YX，ZHANG X，et al. Hepatic stellate cells modulate the differentiation of bone marrow mesenchymal stem cells into hepatocyte-like cells[J]. J Cell Physiol，2008，217（1）:138-144.
[27] POTAPOVA，IA，GAUDETTE GR，BRINK PR，et al. Mesenchymal stem cells support migration，extracellular matrix invasion，proliferation and survival of endothelial cells in vitro[J]. Stem Cells，2007，25（7）:1761-1768.
[28] SADAT S，GEHMERT S，SONG YH，et al. The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF[J]. Biochem Biophys Res Commun，2007， 363（3）:674.
[29] SHAFRITZ DA，OERTEL M，MENTHENA A，et al. Liver stem cells and prospects for liver reconstitution by transplanted cells[J]. Hepatology，2006，43（2 Suppl 1）:S89-98.
[30] MATUSHANSKY I，HERNANDO E，SOCCI ND，et al. Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway[J]. J Clin Invest，2007，117（11）:3248-3257.
[31] SUNDIN M，ORVELL C，RASMUSSON I，et al. Mesenchymal stem cells are susceptible to human herpes viruses，but viral DNA cannot be detected in the healthy seropositive individual[J]. Bone Marrow Transplant，2006，37（11）:1051-1059.
[32] BREITBACH M，BOSTANI T，ROELL W，et al. Potential risks of bone marrow cell transplantation into infarcted hearts[J]. Blood，2007，110（4）:1362-1369. |
