Abstract: Objective This study was conducted to observe the efficacy of laparoscopic assisted hemangioma removal and anatomical hepatectomy in the treatment of patients with huge hepatic hemangioma (HH). Methods 68 patients with huge HH were encountered in our hospital between January 2020 and June 2022, and the enrolled patients had HH with diameter ≥ 10 cm. They were divided into two groups, with 34 cases in each, receiving laparoscopic peeling off tumors or anatomical hepatectomy for removal of the tumors. The BK-200 automatic biochemical analyzer was used to detect the liver function tests. Results The operation time, intraoperative blood loss, peritoneal drainage and hospitalization cost in patients with peeling off tumor treatment were (144.6±37.2)min, (402.3±132.5)mL, (257.2±48.6)mL and (32000±700) yuan, all significantly shorter or less than in patients receiving anatomical hepatectomy; at day three after operation, serum alanine aminotransferase and aspartate aminotransferase levels in patients receiving peeling off tumors were (71.6±14.8)U/L and (48.8±9.2)U/L, both significantly lower than in patients underwent anatomical hepatectomy; post-operationally, the incidence of complications, such as pleural effusion, incision liquefaction or infection and biliary leakage in patients receiving peeling off tumors was 17.6%, not significantly different compared to 26.5% in patients underwent anatomical hepatectomy (P＞0.05). Conclusion The laparoscopic assisted hemangioma peeling and anatomical hepatectomy in treatment of patients with giant HH are both efficacious, and we recommend the peeling off operation, which might shorten the operation time, reduce blood loss with less liver injury.

Key words: Hepatic hemangioma, Laparoscope, Hemangioma peeling, Anatomic hepatectomy, Therapy